Causative Microorganism Association with Outcome in Cardiac Surgery Patients with Infective Endocarditis

Activity: Talk or presentation types › Oral presentation

Description

Infective endocarditis is an inflammation of the inner layer of the heart by infectious etiology and usually is associated with poor clinical outcomes. However, the etiology can differ, where the most common causative agents in the developed world are S.aureus, Streptococcus spp., E.faecalis, and coagulase-negative staphylococci. . In this retrospective study 253 patient medical records were analyzed who underwent cardiac surgery between the years 2016 and 2020 at Pauls Stradins Clinical University Hospital.. One hundred forty-four patients underwent cardiac surgery due to S.aureus, Streptococcus spp., E.faecalis, or coagulase-negative staphylococci-caused infective endocarditis. The rate of blood culture-negative infective endocarditis was 35.17 %. Although S.aureus endocarditis patients had the highest intrahospital mortality rate, statistically significant differences were not found. However, one-year mortality (p=0.049) and three-year mortality (p=0.03) rates were indicating a significantly worse prognosis for S.aureus endocarditis patients. The highest rate of embolic complications were also observed in S.aureus endocarditis patients group. Coagulase-negative staphylococci were the most frequent causative microorganism in the patients with prosthetic valve endocarditis (p=0.015). There were significantly more perivalvular complications observed in the coagulase-negative staphylococci group (p=0.024).. Among the most common causative agents of infective endocarditis S.aureus is associated with the worse long-term prognosis and the highest rate of embolic complications. Coagulase-negative staphylococci were associated with prosthetic valve endocarditis and perivalvular complications.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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