Chronic Kidney Disease and Cerebrovascular Pathology – Incidence and Functional Outcome in Riga East University Hospital

Activity: Talk or presentation types › Poster presentation

Description

The aim of this study was to investigate the incidence of cerebrovascular pathology in patients with chronic kidney disease and its effect on functional outcomes. . In a retrospective cross-sectional study (2018-2020) was analyzed acute hemorrhagic and ischemic stroke patient medical records with concomitant chronic kidney disease who received treatment in Riga East University Hospital Stroke Unit. Data was analysed using IBM SPSS 26.0. Kruskall Wallis, Man Whitney U Test and Spearman’s rank correlation coefficient were used. . Final sample consisted of 305 acute cerebrovascular pathology patients (56.4% females). Overall, 57.3% of stroke patients had second stage chronic kidney disease with average serum creatinine levels 104.3 mmol/l (±32.8). The functional outcome of the stroke depended on the stage of chronic kidney disease. There was statistically significant nonlinear correlation between glomerular filtration rate and NIHSS score on admission (Rho -0.194, p=0.016), glomerular filtration rate and NIHSS score on discharge (Rho -0.186, p=0.020) as well as glomerular filtration rate and mRS on admission (Rho -0.237, p=0.003) and discharge (Rho – 0.224, p=0.05). Mean NIHSS score of ischemic stroke patients on admission was 8,3 ± 5,9, on discharge - 6,5 ±5,8. In hemorrhagic stroke patients group mean NIHSS score on admission was 9,5 ± 7,3, on discharge – 7,1± 6,9. On average 34% of ischemic stroke patients had mRS score 5 on admission, while in hemorrhagic stroke patient’s group – 41%. There was not found a statistical difference between glomerular filtration rate and thromolysed/non-thrombolysed patients groups (Mann Whitney U Test= 1457, p=0.794). . Chronic kidney disease is an important predictor of the severity and functional outcome of a stroke, furthermore the early management and prevention of complications should be a top priority in the prophylaxis of this cerebrovascular pathology.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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