Comparison of Known Risk Factors for Type 1 Diabetes Development in Association with SARS-CoV-2 Virus Exposure

Activity: Talk or presentation types › Poster presentation

Description

Since the beginning of the COVID-19 pandemic, many medical centres have reported an increase in the incidence of primary diagnosed Type 1 diabetes (T1D) in paediatric population. The aim of this study was to evaluate the impact of previously known risk factors for new-onset T1D development in association with SARS-CoV-2 infection.. In this cross-sectional study data of 90 patients diagnosed with new-onset T1D was analysed using the Children’s Clinical university hospital (CCUH) database. Patients were divided into two respective groups of those exposed and non-exposed to COVID-19 infection. MS Excel and IBM SPSS Statistics were used for data compilation and analysis.. From all analysed risk factors in patient groups of non-exposed versus exposed to SARS-CoV-2 infection, it was determined that there was no statistically significant association of D vitamin level for both groups (p=0.176). Positive family history for T1D was more commonly observed in the non-exposed 15.4% (n=8) versus the exposed 3.5% (n=2) group, however this risk factor was not statistically significant for both groups (p=0.181). Mothers of 72.5% (n=37) non-exposed and 75.7% (n=28) exposed patients were older than 25 years old at the time of pregnancy, but no association was found for development of T1D (p>0.999). Cow milk consumption before 6 months of age was more common in non-exposed group 80.8% (n=21) versus exposed 42.1% (n=16) and showed statistically significant difference (p=0.002).. We conclude that many known risk factors (D vitamin level, family history of T1D, mothers age of more than 25 years during pregnancy) did not have statistically significant difference in patients exposed and non-exposed to SARS-CoV-2 infection. However, early introduction of cow milk in infants’ diet was significantly more common in non-exposed group, suggesting that there could be other impact factors associated with T1D development since the start of the pandemic. The research will be continued.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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