Detection Rate of Prostate Cancer in Systematic Compared to Targeted Cores by Transperineal Targeted MRI Fusion Prostate Biopsy in Patients with a History of Negative Transrectal Prostate Biopsy

Activity: Talk or presentation types › Poster presentation

Description

Nowadays a targeted transperineal MRI Fusion prostate biopsy is a technique of choice in the verification of prostate cancer recommended by the European Association of Urology. There is still a debate about the most accurate biopsy protocol. The objective of the study is to verify if targeted cores (TC) are sufficient enough to precisely diagnose prostate cancer in patients with a history of negative transrectal biopsies.. A retrospective study - one center experience. The study included patients who underwent a transperineal software MRI/US Fusion biopsy from year 2019 to 2022. The patients had a history of negative transrectal prostate biopsy and prior to the transperineal biopsy underwent an mpMRI with a PIRADS 3 score and higher. . A total of 120 patients data were analyzed. A mean age 66 y (range 48-83), PSA 12.72 ng/ml (1.36-82), PSAD 0.26 (0.04-1.6), prior biopsies 1.45 (1-5), time from last biopsy 26.1 mo (2-108). Prostate cancer was detected in 76 patients (65 %) of which 54 cases (71.05%) were positive in TC only, 22 (28.95%) in both TC and SC. Comparing ISUP Grade between TC and SC in 22 patients, grade was higher in targeted cores in 13 patients (59.09 %), identical grade in 8 patients (36.36 %), lower grade in 1 patient (4.55%). In 2 cases (1.7%) prostate cancer was detected only by SC. Mean number of SC were 9.07 (range 3-27).. Our study results show that SC can be omitted during targeted transperineal MRI Fusion biopsy in patients with prior negative transrectal biopsy. It does not affect the overall detection rate of clinically significant prostate cancer.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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