Effect of Metabolic Syndrome on Microcirculatory Function in Psoriatic Patients

Activity: Talk or presentation types › Poster presentation

Description

Metabolic syndrome (MetS) includes such factors as obesity, elevated blood pressure, and distorted lipid- and glucose metabolism. It is well known that psoriasis and the metabolic syndrome separately are risk factors for systemic microvascular dysfunction. The metabolic syndrome has been associated with psoriasis and according to publications psoriatic patients, have at least twice the risk of developing metabolic comorbidities compared with the general population. We aimed to find out whether there is a significant effect on microvascular function in psoriatic patients with and without MetS.. MetS factors were analysed for 34 patients (46 ± 12 yr) with moderate to severe psoriasis vulgaris. MetS was defined using the National Cholesterol Education Program Adult Treatment Panel III criteria. MetS were positive for 13 patients (MetS group) and negative for 21 patients (non-MetS group). Blood flow (PU, perfusion units) in psoriatic and normal skin was measured by a single-channel Laser Doppler blood flowmeter (Blood Flowmeter, ADInstruments Ltd., Oxford, UK). Post-occlusive reactive hyperaemia (% changes from basal flow) was assessed on the plaque (psoriatic) and non-plaque (normal) site.. There was no group difference in basal blood flow and postocclusive hyperemia test in psoriatic skin. However data of normal skin showed statistically lower postocclusive hyperemia in MetS group compared with non-MetS (5 % vs 53%, p
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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