Evaluation of Antimicrobial and Defence Proteins in Samples of Primary and Recurrent Nasal Polyps

Activity: Talk or presentation types › Oral presentation

Description

To investigate the complex appearance, relative distribution and interlinks of β-defensin-2, β-defensin-3, β-defensin-4 and cathelicidin LL37 in case of primary and recurrent nasal polyps.. Study group consisted of 29 samples from patients with primary CRSwNP and 19 patients with recurrent nasal polyps. Samples were collected during functional endoscopicsinus surgery (FESS). Control group consisted of 17 normal healthy nasal mucosa samples gathered during routine septoplasty. Tissue β-defensin-2, β-defensin-3, β-defensin-4 and cathelicidin LL37 were detected by immunohistochemical analysis. The results were evaluated by using semi- quantitative method and analysed with the help of Spearman’s rank correlation and Mann-Whitney U test.. Group with primary nasal polyps demonstrated significantly decreased number of β-defensin-2 (p
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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