High-drug-loaded immediate-release tablets of caffeine prepared by twin-screw melt granulation with mannitol

Elzbieta Maria Buczkowska (Speaker)
Kukuls, K. (Co-author)
Horvath, Z. M. (Co-author)
Alīna Jaroslava Frolova (Co-author)
Pētersone, L. (Co-author)
Mohylyuk, V. (Co-author)

Lead Researcher Group

Activity: Talk or presentation types › Poster presentation

Period	23 Mar 2026 → 26 Mar 2026
Event title	15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
Event type	Meeting
Conference number	15
Location	Prague, Czech RepublicShow on map
Degree of Recognition	International

Keywords

solid dosage forms
oral dosage forms
immediate-release
tablets
high-drug-loaded
twin-screw melt granulation
mannitol
caffeine
granulation
continuous
manufacturing
mechanical properties
tensile strength

Field of Science

2.5 Materials engineering
2.4 Chemical engineering
1.4 Chemical sciences
3.3 Health sciences
3.5 Other medical sciences

Related content

Projects
Suitability of sugar alcohols (polyols) as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties
Project: Consolidation grants

Activities
Design space for naproxen amorphous solid dispersion formulations using a solvent method
Activity: Talk or presentation types › Poster presentation
Combined pre-formulation approach for the selection of naproxen-polymer-solvent candidates for the preparation of amorphous solid dispersion
Activity: Talk or presentation types › Poster presentation
Dissolution-permeation approach for biopharmaceutical evaluation: a feasibility study using naproxen
Activity: Talk or presentation types › Poster presentation

Publications
High-drug-loaded immediate-release tablets of caffeine prepared by twin-screw melt granulation with mannitol
Research output: Contribution to conference › Poster › peer-review
Dissolution-permeation approach for biopharmaceutical evaluation: a feasibility study using naproxen
Research output: Contribution to conference › Poster
Ternary Phase Diagrams of Naproxen with Soluplus® and Chloroform or Ethyl Acetate
Research output: Contribution to conference › Poster › peer-review