Impact of the SARS-CoV-2 Pandemic on Clinical Manifestations and Neurophysiological Finding of Guillain-Barré Syndrome

Activity: Talk or presentation types › Poster presentation

Description

Despite the fact that SARS-CoV-2 pandemic has ended, the long term impact data is still scarce. Guillain-Barré syndrome is an autoimmune disease that can develop after inections, including respiratory viruses. The impact that SARS-CoV-2 has on nervous system is still unclear, so this research aims to provide insight – has Covid-19 pandemic changed Guillain-Barré syndrome? . Patients hospitalised in PSKUS in the time period from 2018 to 2022 and discharged with diagnosis Guillain-Barré syndrome were included in the research (2018 to 2022 were categorised before the pandemic, 2021 and 2022 – after). Biometrical data, clinical presentation, cerebrospinal fluid analysis and electrophysiological findings on total 19 patients were gathered. . On average in the span of one year 4 patients were admitted before, and 3,5 after the start of covid pandemic. On average before covid patients were 55,5 years old, mostly men ( woman 16,6 % (N=2), men 83,4% (N=10)), while after – on average 52 years old, 57,1% women (N= 4). After the start of the pandemic for one of the patients the trigger behind Guillain-Barré syndrome was identified as ARVI, and only one of the patients had proven connection with SARS-CoV-2 – virus was contracted after admission in PSKUS. No significant difference was found between clinical Guillain-Barré syndrome presentation and neurophysiological findings. Even after the pandemic electroneurographic studies were still conducted to majority of patients. . Further research on relations between SARS-CoV-2 and Guillain-Barré syndrome is needed. The main focus on additional studies will be patients with the same diagnosis in RAKUS, electrophysical data and vaccination status.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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