Is Cerebral Deoxygenation Associated with Poor Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage?

Activity: Talk or presentation types › Poster presentation

Description

Morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH) reaches up to 60% in first 6-months. Current evidence does not support use of regional cerebral oximetry (rSO2) in clinical decision making. Our aim was to observe the impact of cerebral desaturation detected by rSO2 to outcome in patients with aSAH. . From January 2020 to September 2022 cerebral rSO2 was provided to 23 aSAH intensive care patients Riga, Latvia. Monitoring was started within first 72 hours after ictus and continued up to 7 days. Cerebral deoxygenation was defined as cerebral rSO2 reduction >20% from baseline for at least 30 minutes. As an outcome we analysed the impact of cerebral desaturation to intrahospital mortality and degree of disability according to modified Rankin Scale (mRS) on the day of check-out.. In our preliminary study totally 23 patients (74% females) with mean age of 62±11 years was analysed with median Glasgow Coma Scale 13 points (5-15) at admission. Overall mortality was 35%. Cerebral deoxygenation occurred in 57% of cases. Three quarters of died patients (75%) presented cerebral deoxygenation vs. those who survived (46%), but without statistical significance; p=0.19. In surviving patients with poor neurological outcome (mRS 4-5), cerebral deoxygenation was fixed in 56% vs. 33% with good neurological outcome (mRS 1-3) (p=0.4). Good functional outcome of survivors was in 40% (mRS 1-3), but in 60% mRS was 5 points. . However not direct impact of cerebral deoxygenation detected by cerebral rSO2 was found on outcome, results showed that cerebral rSO2 as an additional tool in multimodal neuromonitoring may provide predictive information for outcome in aSAH patients since most of patients those who died had cerebral deoxygenation during the first week.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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