Description
Sexually transmitted infections (STIs) can be caused by different pathogens. Ureaplasma and Mycoplasma are naturally present in the urinary and reproductive tract of humans, however they can spread and cause STIs. Ureaplasma is one of the most common STIs pathogen worldwide. The rapid diagnosis of the STIs pathogens and timely treatment are essential. Multiplex PCR is a sensitive method for rapid and precise diagnosis of STIs pathogens.The aim of the study was to analyse C.trachomatis, Ureaplasma, M.hominis and M.genitalium prevalence in the NRL of Latvia 2020-2022.. Overall 3563 clinical (urogenital, rectal or oropharyngeal swabs, conjunctival discharge, prostate gland secretion, urine) samples were collected through regular screening or for confirmation of STIs and tested by real time multiplex PCR (AmpliSensC.trachomatis, Ureaplasma, M.hominis, M.genitalium Multiplex PCR kit) - 1484 in 2020, 1087 in 2021 and 992 in 2022. DNA was extracted by the NucliSens EasyMAG (BioMerieux) automated system.
. Positive for at least one pathogen were 1500/3563 (42.1%) of tested clinical samples. Ureaplasma positive were 983/1500 (65.5%) – 334/499 (66.9%) in 2020, 341/535 (63.7%) in 2021 and 308/466 (66.1%) in 2022. Combination Ureaplasma/M.hominis positive were 205/1500 (13.7%) – 84/499 (16.8%) in 2020, 57/535 (10.7%) in 2021 and 64/466 (13.7%) in 2022. M.hominis positive were 137/1500 (9.1%) - 45/499 (9.0%) in 2020, 71/535 (13.3%) in 2021 and 21/466 (4.5%) in 2022. M.genitalium positive were 65/1500 (4.3%) - 8/499 (1.6%) in 2020, 27/535 (5.0%) in 2021 and 30/466 (6.4%) in 2022. C.trachomatis positive were 110/1500 (7.3%) - 28/499 (5.6%) in 2020, 39/535 (7.3%) in 2021 and 43/466 (9.2%) in 2022. . Ureaplasma was the most frequently detected pathogen with similar prevalence in all periods. The second most distributed pathogens were combination of Ureaplasma and M.hominis. Prevalence of M.genitalium and C.trachomatis increased during analysed period, however rate of M.hominis decreased in 2022.
| Period | 27 Mar 2023 → 31 Mar 2023 |
|---|---|
| Event title | RSU Research Week 2023: Research Week 2023 Rīga Stradiņš University |
| Event type | Conference |
| Organiser | Riga Stradins University |
| Location | Riga, LatviaShow on map |
| Degree of Recognition | International |