Pilot Project of Platelet-Rich Fibrin Membrane Tympanoplasty

Activity: Talk or presentation types › Oral presentation

Description

Introduction: Conventionally myringoplasty is a relatively long surgery requiring general anaesthesia. There is a need for faster and less invasive methods, especially in the pediatric praxis. Usually, the defect of the tympanic membrane is repaired with an autologous (cartilage, perichondrium or fascia) tissue patch. Platelet-rich fibrin (PRF) membrane tympanoplasty is a novel procedure with the potential to replace conventional myringoplasty.Objectives. Test and introduce a new tympanoplasty method in otorhinolaryngology.. We performed PRF tympanoplasty on 3 patients from Children Clinical University hospital with residual tympanic membrane perforation longer than 3 months after tympanostomy tube removal.To make a PRF membrane, we use a Couchroun centrifuge and patented A-PRF vacutainers to get PRF membrane. A 20 ml blood sample from the patient was obtained and centrifuged in the A-PRF vacutainer for 14 minutes and then exposed to the PRF pressure box for 4 minutes. Then the myringoplasty procedure was done under general anaesthesia but without harvesting any additional tissues and avoiding other further cuts. The total surgical time, full-time staying in the hospital, and the healing of the tympanic membrane after 2 weeks were registered and compared with average results from conventional tympanoplasty. . From December 2022 till now - 3 patients - 2 girls, 1 boy. Mean age 7 years.Average size of the defect < 25 %. Length of the operation – 15 minutes. Hospitalization time – 4,1 hours. After the follow up in the one patient there was fully healed, in the one 50 % improvement, in one without improvement... The first results of PRF membrane tympanoplasty showed encouraging results suggesting the possible replacement of conventional tympanoplasty with the minimally invasive PRF graft procedure.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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