Sequelae Rate after Tick-borne Encephalitis in Latvia

Activity: Talk or presentation types › Poster presentation

Description

Tick-borne encephalitis (TBE) is a viral infectious disease affecting the central nervous system in many parts of Europe and Asia. Post-encephalitic syndrome (PES) and sequelae of TBE may cause long-lasting morbidity which often impacts on patients’ quality of life.  The aim was to evaluate the sequelae rate and severity of PES after TBE in Latvia. To characterize the sequelae after TBE.. A preliminary data of a prospective follow-up study of TBE in Latvia in the period from 2018-2022. PES was defined with the presence of ≥2 subjective symptoms (headache, memory/concentration disorders, fatigue, arthralgias/myalgias, emotional lability, sleep disorders, dizziness) or with ≥1 objective neurological sign (tremor, spinal nerve paresis, hearing loss/tinnitus, vision disturbances) classified as mild, moderate or severe. Karnofsky index, mRankin scale and EQ5DY were calculated to define the influence on the patients’ quality of life. Statistical data processing with MS Excel and SPSS.. By the 1st of January 2023 total 16 patients with previous TBE were evaluated after the median time 38.41 month (SD 11.86). The PES was found in eleven (68.8%) patients, with mild sequelae in ten (90.9%), moderate in one (9.1%) and no severe sequelae. There were ten cases of menigitis (62.7%) and one meningoencephalitis of patients with PES. The most common symptoms/signs of PES were sleep disorders in eight (72.7%), emotional lability in seven (63.6%) and tremor in six (54.5%) patients. Karnofsky scale (IQR) was 90.0 (70.0-100.0) and 100.0 (90.0-100.0) (p=0.067), mRS (IQR) was 1 (0-2) and 0 (0-0) (p=0.01) in PES and non-PES patients respectively. Quality of life was disturbed in six (54.5%) PES patients concerning EQ5DY scale.. The PES was found in 68.8% patients after TBE. Patients with meningoencephalitis might be more predisposed to PES. Sleep disorders, emotional lability and tremor were the most common sequelae. The PES impacts on patients’ quality of life.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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