Susceptibility Profile of Streptococcus Agalactiae Isolated from Patients with Urinary Tract Infection

  • Skrode, E. (Speaker)
  • Žanis Bordo (Co-author)
  • Storoženko, J. (Co-author)
  • Marija Dončaka (Co-author)
  • Jana Osīte (Co-author)
  • Elza Vazdiķe (Co-author)
  • Beatrise Orlova (Co-author)

Activity: Talk or presentation types › Poster presentation

Description

The aim of the study was to examine urine samples from patients with a clinical picture of urinary tract infection and to identify the uropathogen in these samples – Group B streptococcus - Streptococcus agalactiae. On the next step antimicrobial susceptibility testing of S.agalactiae was undertaken.. From 1st January to 15th December 2022 16161 urine samples were microbiologicaly tested for uropathogens. Urine samples were inoculated onto different microbiological media - Columbia agar and Uriselect agar, and the identification of grown microorganisms were made using Bruker MALDI Biotyper sirius one system. The antimicrobial susceptibility testing was done using the Kirby–Bauer methods according to EUCAST guidelines 2022.. In the examination of 16161 urine samples 382 were positive for S.agalactiae. From 382 samples 372 were taken from women and 10 were taken from men. Antimicrobial susceptibility testing results of S.agalactiae showed that 287/382 isolates were susceptible to erythromycin, 89/382 were resistant and 6/382 were susceptible in increased exposure; 307/382 isolates were susceptible to clindamycin, 75/382 were resistant; 372/382 isolates were susceptible to benzylpenicillin, 10/382 were resistant; 375/382 isolates were susceptible to nitrofurantoin, 7/382 were resistant; 66/382 isolates were sensitive to tetracycline, 306/382 were resistant and 10/382 were susceptible in increased exposure; 353/382 were susceptible in increased exposure to levofloxacin and 29/382 were resistant; 174/382 isolates were susceptible to trimethoprim/sulfametoxazol, 206/382 were resistant and 3/382 were susceptible in increased exposure.. Most S. agalactiae isolated from urine samples are sensitive to the main antimicrobial agent used in infection therapy - benzylpenicillin. High resistance to tetracycline and trimethoprim/sulfamethoxazole was observed in the study.
Period29 Mar 2023
Event titleRSU International Research Conference 2023: Knowledge for Use in Practice
Event typeConference
OrganiserRīga Stradiņš University
LocationRiga, LatviaShow on map
Degree of RecognitionInternational

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