Research output per year
Research output per year
Description
Purpose: searching for biomarkers in the diagnostic algorithm of myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). 1) Age and gender data of 134 patients with ME/CFS, as well as the course of the disease. Age and gender data of 54 healthy individuals. 2) Detection of virus (HHV-6, HHV-7, B19) infection (latent or active) markers in peripheral blood of patients with ME/CFS and healthy individuals. 3) Detection of cytokine IFN-y, IL-17A, IL-2, IL-21, IL-23, IL-6, TNF-a levels in plasma samples using Luminex multiplex technology. 4) Detection of antibodies against b2 adrenergic receptors (AdR) and M3/M4 acetylcholine receptors (AChR) using ELISA. 5) Detection of activin B level using ELISA.
| Date made available | 18 Nov 2022 |
|---|---|
| Publisher | Riga Stradins University |
| Temporal coverage | 6 Jan 2020 - 1 Sept 2022 |
| Date of data production | 1 Sept 2022 |
Field of Science
- 3.1 Basic medicine
Keywords
- ME/CFS
- β2AdR antibodies
- AChR antibodies
- HHV-6
- biomarkers
Research output
- 2 Article
-
Biomarkers in the diagnostic algorithm of myalgic encephalomyelitis/chronic fatigue syndrome
Grāvelsiņa, S. (Corresponding Author), Vilmane, A., Svirskis, S., Rasa-Dzelzkaleja, S., Nora-Krūkle, Z., Vecvagare, K., Krumina, A., Leineman, I., Shoenfeld, Y. & Murovska, M., 10 Oct 2022, In: Frontiers in Immunology. 13, 928945.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)27 Downloads (Pure) -
Potential of activin b as a clinical biomarker in myalgic encephalomyelitis/chronic fatigue syndrome (Me/cfs)
Gravelsina, S. (Corresponding Author), Nora‐krukle, Z., Vilmane, A., Svirskis, S., Vecvagare, K., Krūmiņa, A. & Murovska, M., 11 Aug 2021, In: Biomolecules. 11, 8, 9 p., 1189.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)7 Downloads (Pure)
Projects
- 1 Finished
-
Selection of biomarkers in ME/CFS for patient stratification and treatment surveillance / optimisation
Murovska, M. (Project leader), Berķis, U. (Leading expert), Krūmiņa, A. (Expert), Svirskis, Š. (Expert), Grāvelsiņa, S. (Expert (PhD student)), Arāja, D. (Expert (PhD student)), Vilmane, A. (Expert (PhD student)), Vecvagare, K. (Expert (PhD student)), Maksimova, I. (Participant) & Vārna, V. (Participant)
1/01/20 → 30/06/23
Project: Fundamental and Applied Research Programme