Projects per year
Organisation profile
Organisation profile
The Department of Human Physiology and Biochemistry offers Physiology, Medical Chemistry and Biochemistry courses in various study programs such as Medicine and Biomedicine as well as in Dentistry, Pharmacy, Rehabilitation programmes.
Fields of activity: (A) Qualitative organisation and implementation of undergraduate studies in human physiology, medical chemistry and medical biochemistry within the study programmes of the Faculty of Medicine and other faculties, as well as the management of the Biomedicine master’s study programme; (B) Development of doctoral theses; (C) Implementation of scientific research carried out by the department's academic staff including research conducted in cooperation with RSU clinical.
Research areas: (1) Study of biomarkers (cytokines and growth factors) associated with the pathogenesis of aortic valve stenosis and atherosclerosis. (2) Study of risk factors of diseases associated with obesity (metabolic syndrome, type 2 diabetes). (3) Development of biomarkers and therapeutic drug monitoring as a tool to personalize immunosuppressive therapy in kidney transplant recipients. (4) Development of screening methods by innovative spectroscopy techniques and chemometrics in research of herbal medicine. (5) Various berries and young shoots of extracts obtained by freeze-drying method, the effect of oxidative stress parameters in vitro and in vivo chemical treatment. (6) Enzymology. Impact of polyphenols on metabolism and digestion, and lipid and protein oxidation processes. (7) Study of skin vasomotor and neurovascular reactions in psoriasis patients and patients with other non-contagious skin diseases, including patients with cardiovascular risk factors. (8) Study of biomarkers (cytokines and growth factors) related to SIRS and sepsis, including the development of new diagnostic biomarker panels and clinical approbation. (10) Studies in sports physiology and studies related to fatigue processes.
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Collaborations and top research areas from the last five years
Profiles
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HR, HRV, BP: Fiziskās slodzes ietekme uz fona stresa līmeņa izmaiņām un kognitīvajām spējām
Miķelsone, I. (Project leader) & Jurka, A. (Leading expert)
8/08/24 → 8/08/25
Project: Student projects
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Cancerbeat-2: Physical activity for prevention of breast cancer recurrence: a longitudinal study of molecular mechanisms
Kļaviņa, A. (Project leader), Barone, I. (Expert), Kovtuna, K. (Expert), Čampa, M. (Expert), Vilīte, D. (Assistant (student)), Tretjakovs, P. (Expert) & Reihmane, D. (Expert)
Recovery and Resilience Facility
10/04/24 → 31/03/26
Project: Consolidation grants
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TCReX: Tumour cell response to acute aerobic exercise in breast cancer survivors: modulatory effects of exercise type and intensity
Gersone, G. (Project leader), Reihmane, D. (Work package leader), Kļaviņa, A. (Work package leader), Laizāne, L. (Assistant (student)) & Dela, F. (Project leader)
1/04/24 → 31/03/26
Project: Consolidation grants
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Decoding metabolic connections: the role of salivary amylase activity in modulating visceral fat and triglyceride glucose index
Erta, G. (Corresponding Author), Gersone, G., Jurka, A. & Tretjakovs, P., 18 Mar 2025, In: Lipids in Health and Disease. 24, 1, 7 p., 98.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine
Brangulis, K. (Corresponding Author), Malfetano, J., Marcinkiewicz, A. L., Wang, A., Chen, Y.-L., Lee, J., Liu, Z., Yang, X., Strych, U., Tupina, D., Akopjana, I., Bottazzi, M.-E., Pal, U., Hsieh, C.-L. (Corresponding Author), Chen, W.-H. (Corresponding Author) & Lin, Y.-P. (Corresponding Author), 7 Apr 2025, In: Nature Communications. 16, 1, p. 1-16 16 p., 2898.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Similarities and Differences between Fatigue and Drowsiness
Markovičs, Z., Limba, N. & Eriņš, M., 28 Mar 2025, p. 114. 1 p.Research output: Contribution to conference › Poster › peer-review
Activities
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BMC Public Health (Journal)
Erta, G. (Reviewer of journal article)
3 Jun 2025Activity: Publication peer-review and editorial work types › Publication Peer-review
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Reproductive Biology and Endocrinology (Journal)
Erta, G. (Reviewer of journal article)
2 May 2025Activity: Publication peer-review and editorial work types › Publication Peer-review
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BMC Medicine (Journal)
Erta, G. (Reviewer of journal article)
5 Apr 2025Activity: Publication peer-review and editorial work types › Publication Peer-review
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Press/Media
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Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models
9/04/25
1 item of Media coverage
Press/Media
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HMN 2025: How Alternative strategy to Lyme illness vaccine growth exhibits promise in pre-clinical models
7/04/25
1 item of Media coverage
Press/Media
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Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models
7/04/25
4 items of Media coverage
Press/Media
Equipment
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Frontier FC5916R Centrifuge
Department of Human Physiology and BiochemistryFacility/equipment: Equipment
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iBlot 3 Western Blot Transfer System
Department of Human Physiology and BiochemistryFacility/equipment: Equipment