Projects per year
Organisation profile
Organisation profile
A relatively small but well-shaped group under the scientific direction of Dr. Valentyn Mohylyuk consists of pharmaceutical and chemical scientists, specialists, and one engineer.
Long-term objectives
The long-term objective is to become a world-class research group and intellectual attraction site for academic and industrial collaboration. Thus, we are developing specific directions and facilities to build expertise in pharmaceutical formulation, drug delivery and respective analytical methods.
Research directions
Among the research directions, we are highlighting the following:
· improving the solubility and bioavailability (BA) of poorly soluble drugs of oral dosage forms (ODF),
· optimization of the pharmacokinetics (PK) and custom properties of ODF,
· development of “special” ODF, incl. abuse-deterrent formulation,
· continuous manufacturing stages of solid DF,
· 3D printing and long-acting implants,
· extraction and analytical characterization.
Research techniques
We exploit solid-state characterization, compaction simulation, vacuum-compression-moulding sample preparation, mechanical, particle size distribution, molten materials and liquids rheology, powder and solid dosage form pharmaco-technological characterization, spectroscopic, and chromatographic methods to support our research activities.
Rotor-evaporation, air-jet micronization, high-shear and fluid-bed processing, hot-melt extrusion, vacuum-compression-moulding, roll-compaction, compaction simulation, tableting, fluid-bed and pan coating, capsule-filling, packaging, etc. are part of our technological toolkit.
Group activities
· the development of pharmaceutical technologies and analytical methods, incl. increasing the technology readiness level (TRL),
· close collaboration with international pharmaceutical companies, incl. development of products, technologies, and applications,
· application and performance of scientific projects (national and international level),
· scientific participation in the leading pharmaceutical events (focusing on the group's sci scope),
· supervising PhD and MS students' scientific works,
· collaboration with local and foreign academic institutions, incl. Erasmus programs.
We are open to cooperation
· in the above or related directions,
· in co-application/participation in founded scientific projects,
· build a reputation by publishing in reputable peer-reviewed journals,
· co-participating in prestigious international pharmaceutical events.
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Collaborations and top research areas from the last five years
Profiles
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Innovative dissolution-permeation approach for biopharmaceutical evaluation of hard-to develop oral medicines
Šitovs, A. (Project leader), Pētersone, L. (Expert) & Gurkina, K. (Participant)
16/04/25 → 31/03/26
Project: Consolidation grants
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Deep eutectic solvents: An innovative green approach for Solubility enhancement of poorly water-soluble drugs
Pētersone, L. (Project leader), Mahinovs, R. (Assistant (student)) & Gurkina, K. (Assistant (student))
1/04/25 → 31/03/26
Project: Consolidation grants
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Elucidation of the mechanism of amorphization and dissolution of bad glass former as a function of drug-polymer interaction and preparation method
Mohylyuk, V. (Project leader), Viter, R. (Partner's coordinator), Žogota, M. (Assistant (student)), Horvath, Z. M. (Expert), Kukuls, K. (Expert), Gurkina, K. (Assistant (student)), Bērziņš, A. (Expert), Zabolotnii, V. (Assistant (student)) & Borovskis, A. (Assistant (student))
1/01/25 → 31/12/27
Project: Fundamental and Applied Research Programme
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Amorphous solid dispersion tablet active coating in a perforated pan coater: proof of concept
Raciborska, L., Buczkowska, E. M., Kukuls, K. & Mohylyuk, V. (Corresponding Author), 1 Oct 2025. 1 p.Research output: Contribution to conference › Poster
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Determination of polyols' intrinsic dissolution rate as an important characteristic for pre- and formulation
Buczkowska, E. M., Frolova, A. J., Kukuls, K., Horvath, Z. M., Žogota, M., Pētersone, L. & Mohylyuk, V. (Corresponding Author), Jun 2025. 1 p.Research output: Contribution to conference › Poster
Open AccessFile4 Downloads (Pure) -
Dissolution-Permeation Systems in Biopharmaceutical Research: A Graphical Review on the Current State-of-the-Art
Šitovs, A., Cernisova, V. & Mohylyuk, V. (Corresponding Author), May 2025, In: Journal of Drug Delivery Science and Technology. 107, 106814.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)28 Downloads (Pure)
Datasets
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Loss on Drying (LoD) of Polyols
Frolova, A. J. (Creator), Kukuls, K. (Creator), Horvath, Z. M. (Creator), Gniazdowska, E. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 21 Jan 2025
DOI: 10.48510/FK2/XILW3Z, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/XILW3Z
Dataset
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Intrinsic Dissolution Rate (IDR) of Polyols
Gniazdowska, E. M. (Creator), Frolova, A. J. (Creator), Kukuls, K. (Creator), Horvath, Z. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 6 Feb 2025
DOI: 10.48510/FK2/BJPEC8, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/BJPEC8
Dataset
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Optical Microscopy of Polyols
Kukuls, K. (Creator), Frolova, A. J. (Creator), Horvath, Z. M. (Creator), Gniazdowska, E. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 22 Jan 2025
DOI: 10.48510/FK2/RBPONG, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/RBPONG
Dataset
Prizes
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Letter of Appreciation from the President of the Latvian Academy of Sciences
Bandere, D. (Recipient), Koka, R. (Recipient), Brangule, A. (Recipient), Bārzdiņa, A. (Recipient), Lauberte, L. (Recipient), Mohylyuk, V. (Recipient), Radziņš, O. (Recipient), Teterovska, R. (Recipient), Brante, O. (Recipient), Paulausks, A. (Recipient), Kovalcuka, L. (Recipient), Keidāne, D. (Recipient), Kļaviņa, A. (Recipient) & Ganola, K. (Recipient), Feb 2024
Prize: Honorary award
Activities
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Medical University of Gdańsk
Mohylyuk, V. (Visiting researcher)
3 Nov 2025 → 7 Nov 2025Activity: Visiting an external institution types › Visiting an external academic institution
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International Journal of Pharmaceutics (Journal)
Mohylyuk, V. (Reviewer of journal article)
29 Oct 2025 → 30 Oct 2025Activity: Publication peer-review and editorial work types › Publication Peer-review
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Journal of Drug Delivery Science and Technology (Journal)
Mohylyuk, V. (Reviewer of journal article)
27 Oct 2025Activity: Publication peer-review and editorial work types › Publication Peer-review
Press/Media
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Meet Our Mentor – Dr. Valentyn Mohylyuk, Driving Innovation in Pharmaceuticals
11/08/25
1 item of Media coverage
Press/Media
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Isomalt as PVP-Binder Replacement in High-Shear Wet Granulation for Tablet Preparation – ECP 2025 Poster
9/04/25
1 item of Media coverage
Press/Media
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Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grades of Isomalt – ECP 2025 Poster
8/04/25
1 item of Media coverage
Press/Media