Projects per year
Personal profile
Research interests
Breast cancer organoid cultures, extracellular vesicles, hypoxia, telomere length, multidrug resistence mechanisms, cell differentiation, stem cells
Teaching and supervising interests
Gene engineering, gene therapy, cell therapy, cancer cell research
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
1.6 Biological sciences, Expert, Latvian Council of Science
6 May 2021 → 5 May 2024
1.6 Biological sciences, Expert, Latvian Council of Science
1 Oct 2018 → 30 Sept 2021
1.6 Biological sciences, Expert, Latvian Council of Science
19 Sept 2015 → 17 Sept 2018
External positions
Technical expert, Latvian National Accreditation Bureau
1 Jan 2019 → …
Field of Science
- 3.1 Basic medicine
- 1.6 Biological sciences
Keywords
- breast cancer cells
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Hypoxia-induced molecular alterations in triple negative breast cancer cell lines
Čakstiņa-Dzērve, I., Pirsko, V. & Mitre, I.
1/04/22 → 31/03/23
Project: RSU grants
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TERT gēnu saturoša konstrukta iedarbības pārbaude cilvēka šūnu līnijā
Čakstiņa-Dzērve, I., Pirsko, V. & Mitre, I.
23/11/21 → 10/07/22
Project: Contract research › R&D project
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Identification of novel endogenous controls for accurate qPCR normalization in 2D v/s 3D triple negative breast cancer cell line model
Jain, N., Cekstere, A. A., Kezika, S., Abbo, B. & Čakstiņa-Dzērve, I.
9/04/21 → 8/04/22
Project: Student projects
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Methodology for application of normal and malignant breast tissue-derived organoid culture as a model for diagnostic extracellular vesicle discovery
Čakstiņa-Dzērve, I., Pirsko, V., Mitre, I., Nitisa, D., Vilne, B. & Jain, N.
1/09/20 → 31/08/21
Project: RSU grants
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Hypoxia associated biomarkers in HER2+ breast cancer cell lines for personalized therapy
Čakstiņa-Dzērve, I., Vilne, B., Pirsko, V., Mitre, I. & Nitisa, D.
1/07/20 → 30/06/21
Project: RSU grants
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Identification of novel endogenous reference genes in 2D and 3D cultures of MDA-MB-436 breast cancer cell line for RT-QPCR normalization
Cekstere, A. A., Jain, N., Abbo, B., Kezika, S., Čakstiņa-Dzērve, I., Nitisa, D., Mitre, I. & Pirsko, V., Mar 2022, p. 41. 1 p.Research output: Contribution to conference › Abstract › peer-review
Open Access -
HER2+ breast cancer specific hypoxia-associated molecular alterations and vulnerabilities in METABRIC cohort – bioinformatic analysis
Pirsko, V., Neiburga, K. D., Vilne, B. & Čakstiņa, I., 24 Mar 2021, p. 97.Research output: Contribution to conference › Abstract › peer-review
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Identification of Novel Endogenous Controls for qPCR Normalization in SK-BR-3 Breast Cancer Cell Line
Jain, N., Mitre, I., Nitisa, D., Pirsko, V. & Čakstiņa-Dzērve, I., 17 Oct 2021, In: Genes. 12, 10, 20 p., 1631.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Downloads (Pure) -
Prolonged mild hypoxia induced alterations in the proteome of triple negative breast cancer cell lines MDA-MB-231 and MDA-MB-436
Pirsko, V., Vorslova, S., König, S., Čakstiņa-Dzērve, I. & Daneberga, Z., 24 Mar 2021, p. 107. 1 p.Research output: Contribution to conference › Abstract › peer-review
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Recapitulation of transcriptomic characteristics of primary breast tumours in patient-derived 3D cultures in vitro
Nitiša, D., Jain, N., Irmejs, A., Pirsko, V. & Čakstiņa, I., 1 Feb 2021, In: Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences. 75, 1, p. 20-24 5 p.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
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Story of experience: Supervisor and SPIG Scholarship Fellow
Inese Čakstiņa-Dzērve (Invited speaker) & Nityanand Jain (Invited speaker)
10 Feb 2023Activity: Talk or presentation types › Invited talk
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SELECT SCIENCE webinar "How to optimize and overcome challenges in vitro oncology models"
Inese Čakstiņa-Dzērve (Participant)
3 Feb 2022Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
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RSU Zinātnieku brokastis
Inese Čakstiņa-Dzērve (Participant)
2 Feb 2022Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
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Genes (Journal)
Inese Čakstiņa-Dzērve (Reviewer of journal article)
19 Jan 2022Activity: Publication peer-review and editorial work types › Publication Peer-review
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SELECT SCIENCE webinar "Applications of high-content imaging in 3D models of disease"
Inese Čakstiņa-Dzērve (Participant)
14 Jan 2022Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
Press/Media
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Jaunā zinātniece pēta krūts vēža šūnas ar mērķi uzlabot ķīmijterapiju
3/10/20
1 item of Media coverage
Press/Media
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Covid-19 ietekmē arī zinātnisko darbu: ilgākā termiņā korekcijas būs
25/03/20
1 item of Media coverage
Press/Media