Projects per year
Personal profile
Research interests
Breast cancer organoid cultures, extracellular vesicles, hypoxia, telomere length, multidrug resistence mechanisms, cell differentiation, stem cells
Teaching and supervising interests
Gene engineering, gene therapy, cell therapy, cancer cell research
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
1.6 Biological sciences, Expert, Latvian Council of Science
6 May 2021 → 5 May 2024
1.6 Biological sciences, Expert, Latvian Council of Science
1 Oct 2018 → 30 Sept 2021
1.6 Biological sciences, Expert, Latvian Council of Science
19 Sept 2015 → 17 Sept 2018
External positions
Technical expert, Latvian National Accreditation Bureau
1 Jan 2019 → …
Field of Science
- 3.1 Basic medicine
- 1.6 Biological sciences
Keywords
- breast cancer cells
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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hip-TNBC: Hypoxia-induced molecular alterations and druggable targets in triple negative breast cancer cell lines - HipTNBC
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Work package leader) & Mitre, I. (Expert)
1/01/24 → 31/12/26
Project: Fundamental and Applied Research Programme
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Chronic hypoxia-induced cell viability and mitochondrial priming assessment in breast cancer cell lines / Hroniskas hipoksijas ierosinātās šūnu dzīvotspējas un mitohondriālās apoptozes noteikšana krūts vēža šūnu līnijās
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Expert), Mitre, I. (Participant) & Cekstere, A. A. (Participant)
3/04/23 → 1/04/24
Project: RSU grants
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Hypoxia-induced molecular alterations in triple negative breast cancer cell lines
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Leading expert) & Mitre, I. (Expert)
1/04/22 → 31/03/23
Project: RSU grants
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TERT gēnu saturoša konstrukta iedarbības pārbaude cilvēka šūnu līnijā
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Expert) & Mitre, I. (Expert)
23/11/21 → 10/07/22
Project: Contract research › R&D project
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Identification of novel endogenous controls for accurate qPCR normalization in 2D v/s 3D triple negative breast cancer cell line model
Jain, N. (Project leader), Cekstere, A. A. (Project leader), Kezika, S. (Project leader), Abbo, B. (Project leader) & Čakstiņa-Dzērve, I. (Leading expert)
9/04/21 → 8/04/22
Project: Student projects
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Identification of novel endogenous reference genes in 2D and 3D cultures of MDA-MB-436 breast cancer cell line for RT-QPCR normalization
Cekstere, A. A., Jain, N., Abbo, B., Kezika, S., Čakstiņa-Dzērve, I. (Scientific Advisor), Nitisa, D. (Scientific Advisor), Mitre, I. & Pirsko, V., Mar 2022, p. 41. 1 p.Research output: Contribution to conference › Abstract › peer-review
Open Access -
HER2+ breast cancer specific hypoxia-associated molecular alterations and vulnerabilities in METABRIC cohort – bioinformatic analysis
Pirsko, V., Neiburga, K. D., Vilne, B. & Čakstiņa, I., 24 Mar 2021, p. 97.Research output: Contribution to conference › Abstract › peer-review
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Identification of Novel Endogenous Controls for qPCR Normalization in SK-BR-3 Breast Cancer Cell Line
Jain, N. (Corresponding Author), Mitre, I., Nitisa, D., Pirsko, V. & Čakstiņa-Dzērve, I. (Corresponding Author), 17 Oct 2021, In: Genes. 12, 10, 20 p., 1631.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)45 Downloads (Pure) -
Prolonged mild hypoxia induced alterations in the proteome of triple negative breast cancer cell lines MDA-MB-231 and MDA-MB-436
Pirsko, V., Vorslova, S., König, S., Čakstiņa-Dzērve, I. & Daneberga, Z., 24 Mar 2021, p. 107. 1 p.Research output: Contribution to conference › Abstract › peer-review
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Recapitulation of transcriptomic characteristics of primary breast tumours in patient-derived 3D cultures in vitro
Nitiša, D., Jain, N., Irmejs, A., Pirsko, V. & Čakstiņa, I. (Corresponding Author), 1 Feb 2021, In: Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences. 75, 1, p. 20-24 5 p.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Fulbright visiting researcher scholarship - Dana Farber cancer institute, Boston, MA, USA
Čakstiņa-Dzērve, I. (Recipient), 1 Jun 2022
Prize: Scholarship
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Activities
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Precision Medicine Networking Forum
Čakstiņa-Dzērve, I. (Moderator)
12 Oct 2023 → 13 Oct 2023Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
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Lectures at summer camp "Alfa"
Čakstiņa-Dzērve, I. (Mentor)
3 Aug 2023Activity: Mentoring and other activity types › Mentoring
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Practical workshop on proposal preparation and project management
Cema, I. (Participant), Nora-Krūkle, Z. (Participant), Groma, V. (Participant), Skuja, S. (Participant), Arāja, D. (Participant), Sokolovska, L. (Participant), Svirskis, Š. (Participant), Pjanova, D. (Participant), Čakstiņa-Dzērve, I. (Participant), Sultanova, A. (Participant) & Čistjakovs, M. (Participant)
26 Jun 2023 → 27 Jun 2023Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
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Biedrība "Sievietes medicīnā"/"Women in Medicine" (External organisation)
Čakstiņa-Dzērve, I. (Member)
3 Jun 2023 → …Activity: Membership types › Membership of NGOs
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2nd Face-to-Face 4.UNCAN.eu Consensus meeting
Čakstiņa-Dzērve, I. (Participant)
22 May 2023 → 23 May 2023Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
Press/Media
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Vēzis kā unikāls bioloģisks organisms ar spēcīgām izdzīvošanas stratēģijām
18/06/24
1 Media contribution
Press/Media
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