Personal profile
Research interests
Breast cancer organoid cultures, extracellular vesicles, hypoxia, telomere length, multidrug resistence mechanisms, cell differentiation, stem cells
Teaching and supervising interests
Gene engineering, gene therapy, cell therapy, cancer cell research
Education/Academic qualification
1.6 Biological sciences, Expert, Latvian Council of Science
6 May 2021 → 5 May 2024
1.6 Biological sciences, Expert, Latvian Council of Science
1 Oct 2018 → 30 Sept 2021
1.6 Biological sciences, Expert, Latvian Council of Science
19 Sept 2015 → 17 Sept 2018
External positions
Technical expert, Latvian National Accreditation Bureau
1 Jan 2019 → …
Field of Science
- 1.6 Biological sciences
- 3.1 Basic medicine
Keywords
- breast cancer cells
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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JA PCM: Joint Action Personalised Cancer Medicine
Irmejs, A. (Partner's coordinator), Čakstiņa-Dzērve, I. (Work package leader) & De Nicolo, A. (Work package leader)
1/11/25 → 31/10/29
Project: EU Programmes › Other
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hip-TNBC: Hypoxia-induced molecular alterations and druggable targets in triple negative breast cancer cell lines - HipTNBC
Čakstiņa-Dzērve, I. (Project leader), Mitre, I. (Expert), Rogoza, O. (Assistant (student)) & Pirsko, V. (Work package leader)
1/01/24 → 31/12/26
Project: Fundamental and Applied Research Programme
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Chronic hypoxia-induced cell viability and mitochondrial priming assessment in breast cancer cell lines / Hroniskas hipoksijas ierosinātās šūnu dzīvotspējas un mitohondriālās apoptozes noteikšana krūts vēža šūnu līnijās
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Expert), Mitre, I. (Participant) & Cekstere, A. A. (Participant)
3/04/23 → 1/04/24
Project: RSU grants
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Hypoxia-induced molecular alterations in triple negative breast cancer cell lines
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Leading expert) & Mitre, I. (Expert)
1/04/22 → 31/03/23
Project: RSU grants
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TERT gēnu saturoša konstrukta iedarbības pārbaude cilvēka šūnu līnijā
Čakstiņa-Dzērve, I. (Project leader), Pirsko, V. (Expert) & Mitre, I. (Expert)
23/11/21 → 10/07/22
Project: Contract research › R&D project
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Selection of Novel Reference Genes for qPCR Normalisation in the MDA-MB-436 Breast Cancer Cell Line
Čekstere, A. A. (Corresponding Author), Jain, N., Abbo, B., Kezika, S., Nitisa, D., Mitre, I. & Čakstiņa-Dzērve, I. (Corresponding Author), Sept 2025, In: Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences. 79 , 3-4, p. 186 - 197Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Precīzi un/vai personalizēti? Divas pieejas mūsdienu medicīnā - cik liela ir atšķirība?
Čakstiņa-Dzērve, I. & Behmane, D., Sept 2025, Medicus Bonus, 80 (septembris/oktobris), p. 20-23.Research output: Contribution to specialist publication › Specialist article › Research
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Identification of novel endogenous reference genes in 2D and 3D cultures of MDA-MB-436 breast cancer cell line for RT-QPCR normalization
Cekstere, A. A., Jain, N., Abbo, B., Kezika, S., Čakstiņa-Dzērve, I. (Scientific Advisor), Nitisa, D. (Scientific Advisor), Mitre, I. & Pirsko, V., Mar 2022, p. 41. 1 p.Research output: Contribution to conference › Abstract › peer-review
Open Access -
Identification of Novel Endogenous Controls for qPCR Normalization in SK-BR-3 Breast Cancer Cell Line
Jain, N. (Corresponding Author), Mitre, I., Nitisa, D., Pirsko, V. & Čakstiņa-Dzērve, I. (Corresponding Author), 17 Oct 2021, In: Genes. 12, 10, 20 p., 1631.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)72 Downloads (Pure) -
HER2+ breast cancer specific hypoxia-associated molecular alterations and vulnerabilities in METABRIC cohort – bioinformatic analysis
Pirsko, V., Neiburga, K. D., Vilne, B. & Čakstiņa, I., 24 Mar 2021, p. 97.Research output: Contribution to conference › Abstract › peer-review
Prizes
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Fulbright visiting researcher scholarship - Dana Farber cancer institute, Boston, MA, USA
Čakstiņa-Dzērve, I. (Recipient), 1 Jun 2022
Prize: Scholarship
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Activities
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Functional Precision Oncology: Methods, Models, and Translational Impact
Čakstiņa-Dzērve, I. (Keynote speaker)
17 Mar 2026Activity: Talk or presentation types › Invited talk
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Zuzanna Styrna
Čakstiņa-Dzērve, I. (Host) & Mohylyuk, V. (Host)
1 Mar 2026 → 30 Jun 2026Activity: Hosting a visitor types › Hosting an academic visitor
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Oslo University Hospital
Čakstiņa-Dzērve, I. (Visiting researcher)
15 Dec 2025 → 16 Dec 2025Activity: Visiting an external institution types › Visiting an external academic institution
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Precīzijas medicīna: kas tā ir un kādi ir tās virzieni
Čakstiņa-Dzērve, I. (Invited speaker)
13 Dec 2025Activity: Talk or presentation types › Invited talk
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Reproduktīvā medicīna Mākslīgā apaugļošana (metodes un pētījumi)
Čakstiņa-Dzērve, I. (Invited speaker)
13 Dec 2025Activity: Talk or presentation types › Invited talk
Press/Media
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Precīzijas medicīna: ko tas nozīmē un kādām slimībām tā palīdz jau šobrīd
8/01/26
1 item of Media coverage
Press/Media
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Latvijas zinātnieki pētī, kādēļ vēža šūnas tik veikli izvairās no nāves
21/11/25
1 item of Media coverage
Press/Media
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Precīzāka diagnostika un ārstēšana – zinātnieki tiecas uz precīzijas medicīnu jeb slimnieku personalizētu terapiju
8/10/25
1 item of Media coverage
Press/Media
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Per- un polifluoralkilvielas (PFAS) – mūžīgais piesārņojums
Martinsone, Ž. & Čakstiņa-Dzērve, I.
17/03/25
1 item of Media coverage
Press/Media