Projects per year
Personal profile
Education/Academic qualification
3.1 Basic medicine, Doctor of Philosophy (PhD), Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
1 Mar 1997 → 10 Jun 2003
Award Date: 10 Jun 2003
1.6 Biological sciences, Doctor of Science, University of Latvia
Award Date: 19 Jan 2001
1.6 Biological sciences, Doctor of Science, August Kirchenstein Institute of Microbiology and Virology
10 Jun 1980 → 20 Dec 1988
Award Date: 20 Dec 1988
1.6 Biological sciences, Master of Science, University of Latvia
1 Sep 1975 → 10 Jun 1980
Award Date: 10 Jun 1980
3.1 Basic medicine, Expert, Latvian Council of Science
19 Dec 2019 → 18 Dec 2022
1.6 Biological sciences, Expert, Latvian Council of Science
26 Nov 2016 → 25 Nov 2019
External positions
Leading Researcher, Riga Stradins University
1 Sep 2008 → 31 Dec 2017
Researcher, Department of Molecular Medicine and Surgery, Karolinska Institute
1 Sep 2006 → 31 Aug 2008
Researcher, post-doctoral, Department of Development and Genetics, Evolutionary Biology Centre (EBC), Uppsala University
1 Sep 2004 → 31 Aug 2006
Researcher, Department of Microbiology, Tumor and Cell Biology, Karolinska Institute
1 Jul 2003 → 31 Dec 2004
Ph.D. Student, Microbiology and Tumor Biology Center (MTC), Karolinska Institute
1 Mar 1997 → 10 Jun 2003
Guest-Researcher, Department of Tumor Biology, Karolinska Institute
1 Mar 1992 → 28 Feb 1997
Researcher, August Kirchenstein Institute of Microbiology and Virology
1 Jul 1980 → 28 Feb 1992
Field of Science
- 3.1 Basic medicine
Keywords
- Cancer cell molecular biology
- B-cell hematological malignancy
- Virology: EBV, HHV-6
- Epigenetics and functional genomics of cancer cell
Fingerprint
Dive into the research topics where Irina Holodņuka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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VirA: Reducing networking gaps between Rīga Stradiņš University (RSU) and internationally - leading counterparts in viral infection-induced autoimmunity research
Murovska, M., Lunga, A., Doniņa, S., Nora-Krūkle, Z., Groma, V., Krūmiņa, A., Rasa-Dzelzkalēja, S. & Holodņuka, I.
1/12/20 → 30/11/23
Project: EU Programmes › Horizon 2020
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Investigation of the chemokine receptors CCR1 and CCR2 and EBV infection aimed on disclosure of new markers that can predict the high risk for progression of chronic lymphocytic leukemia
Holodņuka, I., Kozireva, S., Zvejniece, L., Pavlova, J. & Demida, O.
31/08/18 → 30/11/21
Project: Fundamental and Applied Research Programme
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VACTRAIN: Twinning on DNA-Based Cancer Vaccines
Lunga, A., Issagouliantis, M. & Holodņuka, I.
1/01/16 → 31/12/18
Project: EU Programmes › Horizon 2020
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Investigation of chemokine receptors CCR1 and CCR2 as potential diagnostic markers of B-cell malignancy progression
Holodņuka, I., Kozireva, S., Bariševs, M., Sultanova, A., Čistjakovs, M. & Lejniece, S.
1/01/14 → 31/12/17
Project: Fundamental and Applied Research Programme
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The role of the beta-herpesviruses, HHV-6A, HHV-6B, and HHV-7, in the development of high-grade non-Hodgkin's lymphoma
1/01/09 → 31/12/12
Project: Fundamental and Applied Research Programme
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Analysis of the chemokine receptor CCR1 mutations in patients with chronic lymphocytic leukemia
Zvejniece, L., Rivkina, A., Kurbatska, V., Kistkins, S., Pavlova, J., Leončiks, A., Lejniece, S. & Holodņuka, I., 24 Mar 2021, p. 118.Research output: Contribution to conference › Abstract › peer-review
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CHEMOKINE RECEPTORS CCR1 AND CCR2 ARE UP-REGULATED ON CIRCULATING LEUKEMIC CELLS OF THE UNTREATED CD38+ CLL PATIENTS WITH THE HIGH EBV DNA-COPY LOAD
Kholodnyuk, I., Hippe, L., Rivkina, A., Svirskis, S., Sultanova, A., Kozireva, S., Pavlova, J., Murovska, M. & Lejniece, S., 15 Sep 2021, p. 210. 1 p.Research output: Contribution to conference › Abstract › peer-review
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Delivery of oligonucleotide-based therapeutics: challenges and opportunities
Hammond, S. M., Aartsma-Rus, A., Alves, S., Borgos, S. E., Buijsen, R. A. M., Collin, R. W. J., Covello, G., Denti, M. A., Desviat, L. R., Echevarría, L., Foged, C., Gaina, G., Garanto, A., Goyenvalle, A. T., Guzowska, M., Holodnuka, I., Jones, D. R., Krause, S., Lehto, T., Montolio, M. & 2 others, , 9 Apr 2021, In: EMBO Molecular Medicine. 13, 4, e13243.Research output: Contribution to journal › Review article › peer-review
Open AccessFile42 Citations (Scopus)2 Downloads (Pure) -
EPSTEIN BARR VIRUS INFECTION IN NEWLY DIAGNOSED CD38-POSITIVE AND CD38-NEGATIVE PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA
Kozireva, S., Zvejniece, L., Rivkina, A., Pavlova, J., Murovska, M., Lejniece, S. & Kholodnyuk, I., 15 Sep 2021, p. 218. 1 p.Research output: Contribution to conference › Abstract › peer-review
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Expression of the chemokine receptors CCR1 and CCR2 on the circulating leukemic cells of patients with the high-risk chronic lymphocytic leukemia.
Holodnuka, I., Rivkina, A., Zvejniece, L., Demida, O., Svirskis, S., Kozireva, S., Pavlova, J. & Lejniece, S., 13 Dec 2021, p. P-32. 1 p.Research output: Contribution to conference › Abstract › peer-review
Activities
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CHEMOKINE RECEPTORS CCR1 AND CCR2 ON CIRCULATING LYMPHOCYTES IN UNTREATED CLL PATIENTS WITH ANEMIA AND IMMUNE THROMBOCYTOPENIA
Irina Holodņuka (Speaker)
29 May 2021Activity: Talk or presentation types › Poster presentation
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Inflammatory chemokine receptors in Epstein–Barr virus infection
Irina Holodņuka (Speaker)
24 Mar 2021Activity: Talk or presentation types › Oral presentation
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Proportions of the Peripheral Blood Mononuclear Cells in Patients with Rheumatoid Arthritis
Irina Holodņuka (Speaker)
28 Oct 2021Activity: Talk or presentation types › Oral presentation
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CHEMOKINE RECEPTORS CCR1 AND CCR2 ARE UP-REGULATED ON CIRCULATING LEUKEMIC CELLS OF THE UNTREATED CD38+ CLL PATIENTS WITH THE HIGH EBV DNA-COPY LOAD
Irina Holodņuka (Speaker)
16 Sep 2021Activity: Talk or presentation types › Poster presentation
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Viruses (Journal)
Irina Holodņuka (Reviewer of journal article)
16 Nov 2021 → 5 Jan 2022Activity: Publication peer-review and editorial work types › Publication Peer-review