Research output per year
Research output per year
Personal profile
Research interests
The research interests are related to the study of Lyme disease causing bacteria Borrelia burgdorferi. I am studying Borrelia protein structures and functions with the aim to reveal new details about the pathogenesis of Lyme disease causing agent.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
1.6 Biological sciences, Expert, Latvian Council of Science
2 Mar 2023 → 1 Mar 2026
1.6 Biological sciences, Expert, Latvian Council of Science
18 Jun 2020 → 17 Jun 2023
1.6 Biological sciences, Expert, Latvian Council of Science
22 Apr 2017 → 20 Apr 2020
External positions
Senior researcher, Latvian Biomedical Research and Study Centre
Field of Science
- 3.1 Basic medicine
- 1.6 Biological sciences
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine
Brangulis, K. (Corresponding Author), Malfetano, J., Marcinkiewicz, A. L., Wang, A., Chen, Y.-L., Lee, J., Liu, Z., Yang, X., Strych, U., Tupina, D., Akopjana, I., Bottazzi, M.-E., Pal, U., Hsieh, C.-L. (Corresponding Author), Chen, W.-H. (Corresponding Author) & Lin, Y.-P. (Corresponding Author), 7 Apr 2025, In: Nature Communications. 16, 1, 16 p., 2898.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
CspZ variant-specific interaction with Factor H incorporates a metal site to support Lyme borreliae complement evasion
Brangulis, K. (Corresponding Author), Sürth, V., Marcinkiewicz, A. L., Akopjana, I., Kazaks, A., Bogans, J., Huber, A., Lin, Y.-P. (Corresponding Author) & Kraiczy, P. (Corresponding Author), 13 Dec 2024, (E-pub ahead of print) In: Journal of Biological Chemistry. 47 p., 108083.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)2 Downloads (Pure) -
Meta-analysis of the Vmp-like sequences of Lyme disease Borrelia: evidence for the evolution of an elaborate antigenic variation system
Norris, S. J. (Corresponding Author) & Brangulis, K., 2024, In: Frontiers in Microbiology. 15, 22 p., 1469411.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Structural studies of chromosomally encoded outer surface lipoprotein BB0158 from Borrelia burgdorferi sensu stricto
Brangulis, K. (Corresponding Author), Akopjana, I., Bogans, J., Kazaks, A. & Tars, K., Jan 2024, In: Ticks and Tick-borne Diseases. 15, 1, 9 p., 102287.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure) -
Structure of the Borrelia burgdorferi ATP-dependent metalloprotease FtsH in its functionally relevant hexameric form
Brangulis, K. (Corresponding Author), Drunka, L., Akopjana, I. & Tars, K., Jan 2024, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1872, 1, p. 1-8 8 p., 140969.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)19 Downloads (Pure)
Press/Media
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Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models
9/04/25
1 item of Media coverage
Press/Media
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Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models
7/04/25
4 items of Media coverage
Press/Media
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Engineered Bacterial Proteins Could Offer Lasting Protection From Lyme Disease
7/04/25
2 items of Media coverage
Press/Media
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HMN 2025: How Alternative strategy to Lyme illness vaccine growth exhibits promise in pre-clinical models
7/04/25
1 item of Media coverage
Press/Media