Personal profile
Education/Academic qualification
3.4 Medical biotechnology, Expert, Latvian Council of Science
7 Mar 2024 → 6 Mar 2027
3.1 Basic medicine, Expert, Latvian Council of Science
6 May 2021 → 5 May 2024
External positions
Adviser, Karolinska Institutet
5 Sept 2022 → 4 Sept 2027
Senior Scientist, Karolinska Institutet
1 Jan 2010 → 4 Sept 2022
Field of Science
- 3.2 Clinical medicine
- 3.1 Basic medicine
- 3.3 Health sciences
Keywords
- immunology
- vaccine
- chronic virus infection
- cancer
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Genetic characterization of high-risk human papillomaviruses in Ukraine and Latvia to inform national policy of cervical cancer prevention
Issagouliantis, M. (Project leader)
9/06/25 → 31/12/26
Project: Other projects
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Human papillomavirus genome associated correlates of disease progression and treatment response for cervical neoplasms and cancer
Issagouliantis, M. (Project leader), Jansons, J. (Leading expert), Mitiļdžans, A. (Expert), Spridzāne, A. (Expert), Sokolovska, L. (Expert), Dudorova, A. (Expert (PhD student)) & Kiseļova, V. D. (Assistant (student))
3/01/22 → 30/12/25
Project: Fundamental and Applied Research Programme
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Pathogenicity of human Hepatitis C virus relying on enzymatic properties of viral RNA-dependent RNA-polymerase
Issagouliantis, M. (Project leader), Dudorova, A. (Assistant (student)) & Jansons, J. (Project leader)
1/12/20 → 31/12/21
Project: Fundamental and Applied Research Programme
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EUROPARTNER: Strengthening and spreading international partnership activities of the Faculty of Biology and Environmental Protection for interdisciplinary research and innovation of the University of Lodz
Bryszewska, M. (Project leader), Issagouliantis, M. (Partner's coordinator), Lunga, A. (Administrative manager) & Jansons, J. (Leading expert)
Polish national agency for academic exchange
1/12/18 → 15/04/22
Project: EU Programmes › Cooperation programmes
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LIVE®VAC: New approach to active immunotherapy of Hepatitis C related cancer
Issagouliantis, M. (Project leader)
1/12/18 → 28/02/21
Project: Fundamental and Applied Research Programme
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Persistently high prevalence of HPV16 and rising prevalence of non-16/18 HR-HPV genotypes in cervical pre-cancer and cancer in Latvia in 2016-2024 shape the severity of cervical disease
Sokolovska, L. (Corresponding Author), Biserova, K., Spridzāne, A., Krisane, D., Dudorova, A., Gebrila, S., Krasovska, I., Perminov, D., Orlova, B., Petrovska, M., Jansons, J., Mitiļdžans, A., Nazarovs, J. & Isaguliants, M. (Corresponding Author), Feb 2026, In: Frontiers in Oncology. 15, 1676334.Research output: Contribution to journal › Article › peer-review
Open Access -
New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines
Jansons, J. (Corresponding Author), Avdoshina, D., Dudorova, A., Rubio, E. R., Sokolovska, L., Perminov, D., Lindenberga, I., Nicolai, H., Gebrila, S., Chowdhury, S., Skrastina, D., Nazarovs, J., Palefsky, J. M. & Isaguliants, M. (Corresponding Author), Dec 2025, In: Infectious Agents and Cancer. 20, 1, 51.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Online Conference "Chronic Viral Infections and Cancer, Openings for Vaccines and Cure" VIRCAN2024, Monitoring the Progress
Sokolovska, L. (Corresponding Author), Jansons, J., Buonaguro, F. M. & Isaguliants, M. (Corresponding Author), 2 Sept 2025, In: Vaccines. 13, 9, 940.Research output: Contribution to journal › Article › peer-review
Open Access -
New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines
Jansons, J., Avdoshina, D., Dudorova, A., Rubio, E. R., Sokolovska, L., Perminov, D., Lindenberga, I., Nicolai, H., Gebrila, S., Chowdhury, S., Skrastina, D., Nazarovs, J., Palefsky, J. M. & Issagouliantis, M. (Corresponding Author), 21 May 2025, BioMed Central.Research output: Working paper › Preprint
Open Access -
HPV positive cervical squamous cell carcinomas: association with expression of p16, p53 and Ki67
Nazarovs, J., Biserova, K., Krisane, D., Dudorova, A., Lindenberga, I., Sokolovska, L., Isaguliants, M. & Dubencovs, S., 6 Sept 2024, In: Virchows Archiv. 485, Suppl.1, p. S289-S290 2 p., E-PS-10-071.Research output: Contribution to journal › Meeting Abstract › peer-review
Open AccessFile8 Downloads (Pure)
Activities
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The International Papillomavirus Society (External organisation)
Issagouliantis, M. (Member)
13 Feb 2026 → …Activity: Membership types › Membership of NGOs
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Analysis of the Latvian Human Papillomavirus Type 16 Isolate Whole Genome Sequencing Data from Cervical Carcinomas within the Global Context of Publicly Available Complete HPV16 Genome Sequences
Zrelovs, Ņ. (Speaker), Jansons, J. (Co-author), Spridzāne, A. (Co-author), Sokolovska, L. (Co-author), Biserova, K. (Co-author), Krisane, D. (Co-author), Gebrila, S. (Co-author), Orlova, B. (Co-author), Petrovska, M. (Co-author), Ilinsky, V. (Co-author), Ilinskaya, A. (Co-author), Nazarovs, J. (Co-author), Mitiļdžans, A. (Co-author) & Issagouliantis, M. (Co-author)
26 Mar 2025Activity: Talk or presentation types › Oral presentation
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Complete genome analysis of the human papillomavirus type 16 (HPV16) isolates from cervical carcinomas in Latvia
Zrelovs, Ņ. (Speaker), Jansons, J. (Co-author), Spridzāne, A. (Co-author), Sokolovska, L. (Co-author), Biserova, K. (Co-author), Krisane, D. (Co-author), Gebrila, S. (Co-author), Orlova, B. (Co-author), Petrovska, M. (Co-author), Ilinsky, V. (Co-author), Ilinskaya, A. (Co-author), Nazarovs, J. (Co-author), Mitiļdžans, A. (Co-author) & Issagouliantis, M. (Co-author)
22 Nov 2024Activity: Talk or presentation types › Oral presentation
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Sociodemographic and general health factor association with high-risk human papilloma virus infection in a prospective study of females residing in Riga, Latvia
Kiseļova, V. D. (Speaker), Spridzāne, A. (Co-author), Sokolovska, L. (Co-author), Uzuliņa, I. (Co-author), Orlova, B. (Co-author), Petrovska, M. (Co-author), Mitildzans, A. (Co-author) & Issagouliantis, M. (Co-author)
22 Nov 2024Activity: Talk or presentation types › Oral presentation
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SHIFT IN HIGH RISK HPV GENOTYPES IN CERVICAL LESIONS AND CANCER IN LATVIA
Sokolovska, L. (Speaker), Spridzāne, A. (Co-author), Biserova, K. (Co-author), Krisane, D. (Co-author), Gebrila, S. (Co-author), Orlova, B. (Co-author), Petrovska, M. (Co-author), Lindenberga, I. (Co-author), Perminovs, D. (Co-author), Jansons, J. (Co-author), Mitildzans, A. (Co-author), Nazarovs, J. (Co-author) & Issagouliantis, M. (Co-author)
22 Nov 2024Activity: Talk or presentation types › Oral presentation