Personal profile
Field of Science
- 3.2 Clinical medicine
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Development of genetic testing strategies for hereditary breast and ovarian cancer risk prediction by analysis of spectrum of predisposing mutations and their phenotypic manifestations
Irmejs, A. (Project leader), Maksimenko, J. (Leading expert), Daneberga, Z. (Leading expert), Loža, P. (Expert), Liepiņa, E. E. (Expert), Prušakeviča, A. (Assistant (student)) & Kriķe, N. (Assistant (student))
Recovery and Resilience Facility
1/04/24 → 31/03/26
Project: Consolidation grants
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Development of screening algorithm for high breast cancer risk by analysis of spectrum of predisposing mutations and their phenotypic manifestations
Irmejs, A. (Project leader), Daneberga, Z. (Leading expert), Maksimenko, J. (Leading expert), Loža, P. (Expert (PhD student)), Berga-Švītiņa, E. (Expert (PhD student)), Kuzņecova, E. (Expert (PhD student)), Subatniece, S. (Expert), Liepiņa, E. E. (Participant), Čerņeikina, A. (Participant) & Gržeļahovska, A. (Participant)
7/02/22 → 31/12/29
Project: Contract research › R&D project
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Development of screening algorithm for high breast and ovarian cancer risk by analysis of spectrum of predisposing mutations and their phenotypic manifestations
Irmejs, A. (Project leader), Nakazawa (Miklasevica), M. (Participant), Maksimenko, J. (Participant), Loža, P. (Participant), Līcīte, B. (Participant), Tauvena, E. (Participant), Ukleikins, S. (Participant) & Subatniece, S. (Project leader)
12/07/21 → 11/07/22
Project: RSU grants
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Identification of subgroups for escalating and de-escalating treatment in breast cancer by combined use of clinical-pathological and genomic tests
Irmejs, A. (Project leader), Nakazawa (Miklasevica), M. (Leading expert), Maksimenko, J. (Leading expert), Loža, P. (Expert) & Līcīte, B. (Expert)
1/04/19 → 31/03/20
Project: RSU grants
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Study of the outcomes of primary treatment and risk-reducing manipulations in cases of pathogenic BRCA1 gene germline mutations 5382insC and 4154delA
Loža, P. (Project leader) & Irmejs, A. (Supervisor)
1/10/18 → 4/09/23
Project: PhD projects
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The difference in contralateral breast cancer and ovarian cancer risks for BRCA1 founder variant (c.5266dup, c.4035del) carriers with primary breast cancer
Loža, P. (Corresponding Author), Irmejs, A., Daneberga, Z., Maksimenko, J., Trofimovičs, G., Subatniece, S., Gronwald, J., Lubinski, J. & Gardovskis, J., Dec 2025, In: BMC Cancer. 25, 1, 1769.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
The Transcriptomic Profile Underlying Somatic Monoallelic BRCA1 Inactivation: A Biomarker for Breast Cancer Prognosis
Kuzņecova, E., Nakazawa (Miklasevica), M., Kriķe, N., Šatcs, M., Sīviņa, E., Irmejs, A., Loža, P., Gardovskis, J., Miklaševičs, E. & Daneberga, Z. (Corresponding Author), 14 Aug 2025, In: Diagnostics. 15, 16, 16 p., 2037.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
Difference in Survival Between BRCA1 Pathogenic Variants c.4035del and c.5266dup
Loža, P., Irmejs, A. & Daneberga, Z., Feb 2025, In: Breast. 80, Suppl., 2 p., 104233.Research output: Contribution to journal › Meeting Abstract › peer-review
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Analysis of molecular genetic testing yields for hereditary forms of cancer 2020-2023
Pirushka, I., Lace, B., Mičule, I., Irmejs, A., Loža, P. & Maksimenko, J., Dec 2024, In: European Journal of Human Genetics. 32, p. 1255-1256 2 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Spectrum and frequency of CHEK2 variants in breast cancer affected and general population in the Baltic states region, initial results and literature review
Pavlovica, K. (Corresponding Author), Irmejs, A., Noukas, M., Palover, M., Kals, M., Tonisson, N., Metspalu, A., Gronwald, J., Lubinski, J., Murmane, D., Kalnina, A., Loza, P., Maksimenko, J., Trofimovics, G., Subatniece, S., Daneberga, Z., Miklasevics, E. & Gardovskis, J., May 2022, In: European Journal of Medical Genetics. 65, 5, p. 104477 7 p., 104477.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus)
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Epidemiology of Hereditary Ovarian Cancer
Kriķe, N. (Speaker), Irmejs, A. (Co-author), Loža, P. (Co-author), Daneberga, Z. (Co-author), Miklaševičs, E. (Co-author), Berga-Švītiņa, E. (Co-author) & Kuzņecova, E. (Co-author)
26 Mar 2025Activity: Talk or presentation types › Oral presentation
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Identifying Genetic Factors Associated with Breast or Ovarian Cancer Risk in BRCA1 Pathogenic Variant Carriers
Berga-Švītiņa, E. (Speaker), Loža, P. (Co-author), Maksimenko, J. (Co-author), Vilne, B. (Co-author) & Miklaševičs, E. (Co-author)
29 Mar 2023Activity: Talk or presentation types › Oral presentation
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Spectrum and Frequency of CHEK2 Variants in Breast Cancer in Latvia: Initial Results and Literature Review
Irmejs, A. (Speaker), Pavloviča, K. (Co-author), Maksimenko, J. (Co-author), Mūrmane, D. (Co-author), Loža, P. (Co-author), Daneberga, Z. (Co-author), Miklaševičs, E. (Co-author), Gardovskis, J. (Co-author), Subatniece, S. (Co-author) & Trofimovičs, G. (Co-author)
29 Mar 2023 → 31 Mar 2023Activity: Talk or presentation types › Oral presentation
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Controlateral Breast Cancer and Ovarian Cancer Risks in Cases with Primary Breast Cancer and BRCA1 Pathogenic Variants c.5266dup or c.4039del
Loža, P. (Speaker), Irmejs, A. (Co-author), Maksimenko, J. (Co-author), Miklaševičs, E. (Co-author), Gardovskis, J. (Co-author) & Trofimovičs, G. (Co-author)
29 Mar 2023Activity: Talk or presentation types › Poster presentation
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Ultrasound Guided Neddle Biopsy to Evaluate Nodal Metastasis after Preoperative Systemic Therapy in Different Breast Cancer Subtype Groups
Līcīte, B. (Speaker), Irmejs, A. (Co-author), Maksimenko, J. (Co-author), Loža, P. (Co-author), Trofimovičs, G. (Co-author), Miklaševičs, E. (Co-author), Nazarovs, J. (Co-author), Romanovska, M. (Co-author), Deičmane, J. (Co-author), Purkalne, G. (Co-author) & Gardovskis, J. (Co-author)
29 Mar 2023Activity: Talk or presentation types › Poster presentation
Press/Media
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Pārmantots krūts un olnīcu vēzis: ģenētiskā testēšana, agrīna diagnostika, personalizēta terapija un riska samazināšana
Daneberga, Z., Irmejs, A., Loža, P., Maksimenko, J., Subatniece, S. & Gardovskis, J.
1/02/22
1 item of Media coverage
Press/Media