Personal profile
Teaching and supervising interests
Accepting PhD Students;
support researchers at risk
Research interests
Dr. V. Mohylyuk is a pharmaceutical scientist with industrial and academic experience. He got his BS/MS in Pharm Technology and his PhD degree in Pharm Sci. Since 2002, Dr. V. Mohylyuk has worked for pharmaceutical companies and held positions related to development (pre- and formulation), scale-up, technology transfer, and manufacturing of different dosage forms. His working experience at universities includes research groups at Freie Universität Berlin, the University of Hertfordshire, and Queen's University Belfast. Since 2023, Dr. Valentyn Mohylyuk has been leading the pharmaceutical scientific group at Riga Stradiņš University.
Dr. V. Mohylyuk is mostly focused on solving current challenges and the development of complicated dosage form formulations with tailored drug release, incl. oral taste-masked, immediate-, sustained-, and delayed-release, as well as formulations with enhanced solubility and permeability.
Among the research directions are
- improving the solubility and bioavailability of poorly soluble drugs in oral dosage forms
- optimization of the pharmacokinetics and custom properties of dosage forms
- development of “special” dosage forms, such as abuse-deterrent formulations; continuous manufacturing steps, such as extrusion and roll compaction
- FDM 3D printing, incl. implants
- and repurposing "classical" technological approaches.
Education/Academic qualification
3.1 Basic medicine, Expert, Latvian Council of Science
13 Jul 2023 → 12 Jul 2026
Field of Science
- 2.5 Materials engineering
- 1.4 Chemical sciences
- 2.4 Chemical engineering
- 3.3 Health sciences
- 3.5 Other medical sciences
Keywords
- bioavailability
- formulation
- preformulation
- pharmaceutical technology
- drug delivery
- drug delivery systems
- dosage forms
- granulation
- coating
- compaction
- roll compaction
- tableting
- extrusion
- hot-melt extrusion
- 3D printing
- fusion deposition modeling
- characterisation
- solubility
- dissolution
- amorphization
- solid dispersion
- vacuum compression molding
- rheology
- thermal analysis
- drug loading
- biopharmaceutical
- permeability
- polymers
- films
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 1 No Poverty -
SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 11 Sustainable Cities and Communities -
SDG 12 Responsible Consumption and Production -
SDG 13 Climate Action -
SDG 17 Partnerships for the Goals
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Suitability of sugar alcohols (polyols) as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties
Mohylyuk, V. (Project leader), Buczkowska, E. M. (Leading expert), Pētersone, L. (Leading expert), Žogota, M. (Expert), Horvath, Z. M. (Participant), Kukuls, K. (Participant) & Frolova, A. J. (Participant)
1/04/24 → 31/03/26
Project: Consolidation grants
-
Elucidation of the mechanism of amorphization and dissolution of bad glass former as a function of drug-polymer interaction and preparation method
Mohylyuk, V. (Project leader), Viter, R. (Partner's coordinator), Žogota, M. (Assistant (student)), Horvath, Z. M. (Expert), Kukuls, K. (Expert), Gurkina, K. (Assistant (student)), Bērziņš, A. (Expert), Zabolotnii, V. (Assistant (student)) & Borovskis, A. (Assistant (student))
1/01/25 → 31/12/27
Project: Fundamental and Applied Research Programme
-
Improving Apparent Solubility and Release Rate of the Model Poorly Soluble Drug via Polymer-Based Composites Fabricated by Electrospinning Technique
Viter, R. (Project leader) & Mohylyuk, V. (Partner's coordinator)
4/09/23 → 31/05/24
Project: Projects outside RSU
-
Effect of the solvent on the formation of solid dispersion of ibuprofen and Hypromellose acetate succinate
Raciborska, L. (Participant), Kukuls, K. (Work package leader), Buczkowska, E. M. (Work package leader) & Mohylyuk, V. (Project leader)
1/07/24 → 31/03/25
Project: Student projects
-
Development of technology for pharmaceutical product
Mohylyuk, V. (Project leader), Pētersone, L. (Work package leader), Žogota, M. (Work package leader), Kukuls, K. (Work package leader) & Buczkowska, E. M. (Project leader)
22/12/23 → 22/12/25
Project: Contract research › R&D project
-
Twin-screw melt granulation with PEG 8000: Effect of binder particle size and processing temperature on the granule and tablet properties
Horváth, Z. M., Petersone, L. & Mohylyuk, V. (Corresponding Author), Sept 2024, In: Advanced Powder Technology. 35, 9, 104585.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Compaction and Structural-Mechanical Properties of Tablets as a Function of Volume Ratios of Excipients
Mohylyuk, V. (Corresponding Author), Paulausks, A., Radzins, O. & Lauberte, L., 19 Mar 2024. 1 p.Research output: Contribution to conference › Poster › peer-review
Open AccessFile20 Downloads (Pure) -
An approach for pH-independent release of poorly soluble ionizable drugs using hot-melt extrusion
Darwich, M., Mohylyuk, V., Kolter, K., Bodmeier, R. & Dashevskiy, A. (Corresponding Author), Oct 2024, In: Journal of Drug Delivery Science and Technology. 100, 106027.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Dwell Time on Tableting: Dwell Time According to Force versus Geometric Dwell Time
Mohylyuk, V. (Corresponding Author), Sept 2024, In: Pharmaceutical Development and Technology. 29, 7, p. 719-726Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Enhancement of itraconazole solubility and release by hot-melt extrusion with Soluplus®
Darwich, M., Mohylyuk, V., Kolter, K., Bodmeier, R. & Dashevskiy, A. (Corresponding Author), Mar 2023, In: Journal of Drug Delivery Science and Technology. 81, 104280.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus)
Datasets
-
Turbidity Test of Polymers in Organic Solvents
Gurkina, K. (Creator), Kačanovs, R. (Creator), Horvath, Z. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 5 Dec 2025
DOI: 10.48510/fk2/nmxlh2, https://doi.org/10.48510/FK2/NMXLH2
Dataset
-
Precipitation Profiles of Naproxen in Dissolution Media
Gurkina, K. (Creator), Kačanovs, R. (Creator), Horvath, Z. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 10 Dec 2025
DOI: 10.48510/fk2/nqenjo, https://doi.org/10.48510/FK2/NQENJO
Dataset
-
BET Surface Area, Pore Volume, and Pore Size Distribution of Polyols
Horvath, Z. M. (Creator), Frolova, A. J. (Creator), Kukuls, K. (Creator), Gniazdowska, E. M. (Creator), Pētersone, L. (Creator), Mohylyuk, V. (Creator) & Buczkowska, E. M. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 29 Sept 2025
DOI: 10.48510/fk2/96wykv, https://doi.org/10.48510/FK2/96WYKV
Dataset
-
Karl Fischer (KF) Titration of Polyols
Frolova, A. J. (Creator), Kukuls, K. (Creator), Horvath, Z. M. (Creator), Buczkowska, E. M. (Creator), Pētersone, L. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 17 Mar 2025
DOI: 10.48510/FK2/4AREIO, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/4AREIO
Dataset
-
Karl Fischer (KF) Titration of Polyols
Frolova, A. J. (Creator), Kukuls, K. (Creator), Horvath, Z. M. (Creator), Gniazdowska, E. M. (Creator), Pētersone, L. (Creator) & Mohylyuk, V. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 17 Mar 2025
DOI: 10.48510/fk2/4areio, https://doi.org/10.48510/FK2/4AREIO
Dataset
Prizes
-
Letter of Appreciation from the President of the Latvian Academy of Sciences
Bandere, D. (Recipient), Koka, R. (Recipient), Brangule, A. (Recipient), Bārzdiņa, A. (Recipient), Lauberte, L. (Recipient), Mohylyuk, V. (Recipient), Radziņš, O. (Recipient), Teterovska, R. (Recipient), Brante, O. (Recipient), Paulausks, A. (Recipient), Kovalcuka, L. (Recipient), Keidāne, D. (Recipient), Kļaviņa, A. (Recipient) & Ganola, K. (Recipient), Feb 2024
Prize: Honorary award
Activities
-
Determination of Intestinal Permeability of Drugs Ex-Vivo
Mohylyuk, V. (Supervisor), Emsiņš, J. (Participant) & Šitovs, A. (Participant)
8 Nov 2023 → 7 Nov 2024Activity: Mentoring and other activity types › Other
-
Pharmaceutics (Journal)
Mohylyuk, V. (Guest Editor)
29 Sept 2024 → 20 Feb 2026Activity: Publication peer-review and editorial work types › Editorial work
File -
Suitability of sugar alcohols as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties
Mohylyuk, V. (Speaker)
21 Apr 2026 → 22 Apr 2026Activity: Talk or presentation types › Oral presentation
File -
Combined pre-formulation approach for the selection of naproxen-polymer-solvent candidates for the preparation of amorphous solid dispersion
Gurkina, K. (Speaker), Kačanovs, R. (Co-author), Horvath, Z. M. (Co-author) & Mohylyuk, V. (Co-author)
23 Mar 2026 → 26 Mar 2026Activity: Talk or presentation types › Poster presentation
-
Effect of microcrystalline cellulose (MCC) type and roll compaction force on the mechanical properties of tablets containing a high dose of poorly compactible substance
Mohylyuk, V. (Speaker), Kukuls, K. (Co-author), Frolova, A. J. (Co-author), Buczkowska, E. M. (Co-author) & Shmyrova, J. (Co-author)
23 Mar 2026 → 26 Mar 2026Activity: Talk or presentation types › Poster presentation
Press/Media
-
Meet Our Mentor – Dr. Valentyn Mohylyuk, Driving Innovation in Pharmaceuticals
11/08/25
1 item of Media coverage
Press/Media
-
Isomalt as PVP-Binder Replacement in High-Shear Wet Granulation for Tablet Preparation – ECP 2025 Poster
9/04/25
1 item of Media coverage
Press/Media
-
Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grades of Isomalt – ECP 2025 Poster
8/04/25
1 item of Media coverage
Press/Media
-
News > FDM 3D-printed oral dosage form of prednisolone – Improvement of printability and influencing drug release
Horvath, Z. M., Grundsteins , K., Radziņš, O., Kons, A., Bērziņš, A., Viter, R., Lamprou, D. A. & Mohylyuk, V.
5/03/25
1 item of Media coverage
Press/Media
-
NEWS> High drug-loaded amorphous solid dispersions of a poor glass forming drug: The impact of polymer type and cooling rate on amorphous drug behaviour
Kolisnyk, T., Mohylyuk, V. & Andrews, G. P.
23/12/24
1 item of Media coverage
Press/Media