Projects per year
Personal profile
Teaching and supervising interests
Accepting PhD Students;
support researchers at risk
Research interests
Dr. V. Mohylyuk is a pharmaceutical scientist with industrial and academic experience. He got his BS/MS in Pharm Technology and his PhD degree in Pharm Sci. Since 2002, Dr. V. Mohylyuk has worked for pharmaceutical companies and held positions related to development (pre- and formulation), scale-up, technology transfer, and manufacturing of different dosage forms. His working experience at universities includes research groups at Freie Universität Berlin, the University of Hertfordshire, and Queen's University Belfast. Since 2023, Dr. Valentyn Mohylyuk has been leading the pharmaceutical scientific group at Riga Stradiņš University.
Dr. V. Mohylyuk is mostly focused on solving current challenges and the development of complicated dosage form formulations with tailored drug release, incl. oral taste-masked, immediate-, sustained-, and delayed-release, as well as formulations with enhanced solubility and permeability.
Among the research directions are
- improving the solubility and bioavailability of poorly soluble drugs in oral dosage forms
- optimization of the pharmacokinetics and custom properties of dosage forms
- development of “special” dosage forms, such as abuse-deterrent formulations; continuous manufacturing steps, such as extrusion and roll compaction
- FDM 3D printing, incl. implants
- and repurposing "classical" technological approaches.
Education/Academic qualification
3.1 Basic medicine, Expert, Latvian Council of Science
5 Mar 2026 → 4 Mar 2029
Award Date: 5 Mar 2026
3.1 Basic medicine, Expert, Latvian Council of Science
13 Jul 2023 → 12 Jul 2026
External positions
Member/expert of the European Pharmacopoeia, European Directorate for the Quality of Medicines and HealthCare (EDQM)
9 Dec 2025 → …
Field of Science
- 2.5 Materials engineering
- 1.4 Chemical sciences
- 2.4 Chemical engineering
- 3.3 Health sciences
- 3.5 Other medical sciences
Keywords
- bioavailability
- formulation
- preformulation
- pharmaceutical technology
- drug delivery
- drug delivery systems
- dosage forms
- granulation
- coating
- compaction
- roll compaction
- tableting
- extrusion
- hot-melt extrusion
- 3D printing
- fusion deposition modeling
- characterisation
- solubility
- dissolution
- amorphization
- solid dispersion
- vacuum compression molding
- rheology
- thermal analysis
- drug loading
- biopharmaceutical
- permeability
- polymers
- films
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 1 No Poverty
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 11 Sustainable Cities and Communities
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SDG 12 Responsible Consumption and Production
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SDG 13 Climate Action
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SDG 17 Partnerships for the Goals
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Suitability of sugar alcohols (polyols) as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties
Mohylyuk, V. (Project leader), Buczkowska, E. M. (Member of project working group), Pētersone, L. (Member of project working group), Žogota, M. (Member of project working group), Horvath, Z. M. (Member of project working group), Kukuls, K. (Member of project working group) & Frolova, A. J. (Member of project working group)
1/04/24 → 31/03/26
Project: Research and development projects financed by the Latvian state budget › Other projects financed by the Latvian state budget
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Elucidation of the mechanism of amorphization and dissolution of bad glass former as a function of drug-polymer interaction and preparation method
Mohylyuk, V. (Project leader), Viter, R. (Partner's coordinator), Žogota, M. (Member of project working group), Horvath, Z. M. (Member of project working group), Kukuls, K. (Member of project working group), Gurkina, K. (Member of project working group), Bērziņš, A. (Member of project working group), Zabolotnii, V. (Member of project working group) & Borovskis, A. (Member of project working group)
1/01/25 → 31/12/27
Project: Research and development projects financed by the Latvian state budget › Fundamental and Applied Research Projects
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Improving Apparent Solubility and Release Rate of the Model Poorly Soluble Drug via Polymer-Based Composites Fabricated by Electrospinning Technique
Viter, R. (Project leader) & Mohylyuk, V. (Partner's coordinator)
4/09/23 → 31/05/24
Project: Projects not classified elsewhere › Projects outside institution
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Development of technology for pharmaceutical product
Mohylyuk, V. (Project leader), Pētersone, L. (Work package leader), Žogota, M. (Work package leader), Kukuls, K. (Work package leader) & Buczkowska, E. M. (Project leader)
22/12/23 → 22/12/25
Project: Contract works and contract research with companies, public persons, private financing and income from intellectual property › Contract research
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Investigation of the composition and preparation process variables on the tabletability and in vitro drug release: focus on the high drug-loaded formulations and poorly soluble drugs
Gurkina, K. (Project leader), Mohylyuk, V. (Supervisor) & Šitovs, A. (Supervisor)
2/02/26 → 2/02/31
Project: Projects not classified elsewhere › PhD project
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PEEK Implants for Cranioplasty: A Mapping Review of 3D Printing, Surface Functionalisation, and Clinical Performance Gaps
Horvath, Z. M., Viter, R., Radziņš, O., Thor, A., Kolisnyk, T. & Mohylyuk, V., 27 Apr 2026, In: Materials Advances. 7, 8, p. 3935-3958Research output: Contribution to journal › Review article › peer-review
Open Access2 Citations (Scopus) -
FDM 3D-printed oral dosage form of prednisolone – Improvement of printability and influencing drug release
Horváth, Z. M., Grundšteins, K., Radziņš, O., Kons, A., Bērziņš, A., Viter, R., Lamprou, D. A. & Mohylyuk, V., 30 Mar 2025, In: International Journal of Pharmaceutics. 673, 14 p., 125391.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)20 Downloads (Pure) -
The Effect of Microcrystalline Cellulose–CaHPO4 Mixtures in Different Volume Ratios on the Compaction and Structural–Mechanical Properties of Tablets
Mohylyuk, V., Paulausks, A., Radzins, O. & Lauberte, L., 5 Mar 2024, In: Pharmaceutics. 16, 3, 362.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)9 Downloads (Pure) -
IVIVC for Extended Release Hydrophilic Matrix Tablets in Consideration of Biorelevant Mechanical Stress
Mohylyuk, V., Goldoozian, S., Andrews, G. P. & Dashevskiy, A., 2020, In: Pharmaceutical Research. 37, 11, 227.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (Scopus) -
Ex vivo permeability study of poorly soluble drugs across gastrointestinal membranes: acceptor compartment media composition
Sitovs, A. & Mohylyuk, V., 13 Sept 2024. 1 p.Research output: Contribution to conference › Poster
Open AccessFile10 Downloads (Pure)
Datasets
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Turbidity Test of Polymers in Organic Solvents
Gurkina, K. (Creator), Kačanovs, R. (Creator), Horvath, Z. M. (Creator) & Mohylyuk, V. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 5 Dec 2025
DOI: 10.48510/fk2/nmxlh2, https://doi.org/10.48510/FK2/NMXLH2
Dataset
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Precipitation Profiles of Naproxen in Dissolution Media
Gurkina, K. (Creator), Kačanovs, R. (Creator), Horvath, Z. M. (Creator) & Mohylyuk, V. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 10 Dec 2025
DOI: 10.48510/fk2/nqenjo, https://doi.org/10.48510/FK2/NQENJO
Dataset
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Ibuprofen Solubility in Eutectic Solvents Formed by Choline-Chloride and Polyols
Mahinovs, R. (Creator), Pētersone, L. (Creator) & Mohylyuk, V. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 29 Apr 2026
DOI: 10.48510/fk2/mr9vst
Dataset
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Inductively Coupled Plasma Mass Spectrometry (ICP-MS) of Japanese Quince Biomass
Pētersone, L. (Creator), Žogota, M. (Creator), Mahinovs, R. (Creator) & Mohylyuk, V. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 29 Apr 2026
DOI: 10.48510/fk2/arnq6j
Dataset
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BET Surface Area, Pore Volume, and Pore Size Distribution of Polyols
Horvath, Z. M. (Creator), Frolova, A. J. (Creator), Kukuls, K. (Creator), Gniazdowska, E. M. (Creator), Pētersone, L. (Creator), Mohylyuk, V. (Creator) & Buczkowska, E. M. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 29 Sept 2025
DOI: 10.48510/fk2/96wykv, https://doi.org/10.48510/FK2/96WYKV
Dataset
Prizes
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Letter of Appreciation from the President of the Latvian Academy of Sciences
Bandere, D. (Recipient), Koka, R. (Recipient), Brangule, A. (Recipient), Bārzdiņa, A. (Recipient), Lauberte, L. (Recipient), Mohylyuk, V. (Recipient), Radziņš, O. (Recipient), Teterovska, R. (Recipient), Brante, O. (Recipient), Paulausks, A. (Recipient), Kovalcuka, L. (Recipient), Keidāne, D. (Recipient), Kļaviņa, A. (Recipient) & Ganola, K. (Recipient), Feb 2024
Prize: Honorary award
Activities
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Determination of Intestinal Permeability of Drugs Ex-Vivo
Mohylyuk, V. (Supervisor), Emsiņš, J. (Participant) & Šitovs, A. (Participant)
8 Nov 2023 → 7 Nov 2024Activity: Mentoring and other activity types › Other
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Pharmaceutics (Journal)
Mohylyuk, V. (Guest Editor)
29 Sept 2024 → 20 Feb 2026Activity: Publication peer-review and editorial work types › Editorial work
File -
Viesturs Karlivāns
Šitovs, A. (Host) & Mohylyuk, V. (Host)
31 Aug 2026Activity: Hosting a visitor types › Hosting a non-academic visitor
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Spectroscopic and morphological evaluation of phase behaviour in naproxen-Soluplus® solvent-cast films prepared from ethyl acetate and chloroform
Horvath, Z. M. (Speaker), Kačanovs, R. (Co-author), Viter, R. (Co-author), Bērziņš, A. (Co-author) & Mohylyuk, V. (Co-author)
26 Aug 2026 → 28 Aug 2026Activity: Talk or presentation types › Poster presentation
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Effect of solvent on the coating parameters and solid state of drug in a polymer film
Mohylyuk, V. (Speaker)
26 Aug 2026 → 29 Aug 2026Activity: Talk or presentation types › Oral presentation
File
Press/Media
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What's Next in Pharmaceutical Science?
Mohylyuk, V. & Black, M.
9/07/26
2 items of Media coverage
Press/Media
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News » Twin-Screw Melt Granulation with Mannitol: High-Drug-Loaded Immediate-Release Tablets of Caffeine
Buczkowska, E. M., Kukuls, K., Horvath, Z. M., Frolova, A. J., Pētersone, L., Dadou, S. & Mohylyuk, V.
17/06/26
1 item of Media coverage
Press/Media
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News » Dissolution-permeation approach for biopharmaceutical evaluation: a feasibility study using naproxen
Šitovs, A., Gurkina, K., Pētersone, L. & Mohylyuk, V.
16/05/26
1 item of Media coverage
Press/Media
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News » Taste-Masked Microparticles of Sodium Warfarin Prepared by Hot Melt Extrusion and Thermal Postprocessing
Kaufelde, P., Aniskevich, A., Sevcenko, J., Žogota, M., Horvath, Z. M. & Mohylyuk, V.
13/05/26
1 item of Media coverage
Press/Media
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News » Effect of microcrystalline cellulose (MCC) type and roll compaction force on the mechanical properties of tablets containing a high dose of poorly compactible substance
Mohylyuk, V., Kukuls, K., Frolova, A. J., Buczkowska, E. M. & Shmyrova, J.
12/05/26
1 item of Media coverage
Press/Media