Clinical, biochemical, immunogenetic paradigms of Covid-19 infection and their correlation with socio-demographic, etiological, pathogenetic, diagnostic, therapeutically and prognostically important factors to be included in guidelines

The aim of the study is to identify socio-demographic, clinical, biochemical, molecular and immunological factors influencing human susceptibility to the virus, diagnosis of the disease, course, treatment results and post-infectious consequences. It is planned to recruit patients with various degrees of COVID-19 severity and also asymptomatic cases of SARS-CoV-2 infection. Data obtained in Latvian population will be important considering differences in spread of the disease and symptoms in various populations. The data will allow to develop clinical algorithms and guidelines, improve diagnosis and treatment efficacy and reduce lethality. Information obtained will allow us to perform comparative analysis with data from other countries and will allow to adapt World Health Organization’s guidelines in Latvia.