Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 3/11/25 → 30/04/26 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure
Keywords
- BCS Class 3
- oral dosage form
- tablets
- bioavailability
- acetaminophen
- absorption
- dissolution
- disintegration
- diluents
- polyols
- lactose
- isomalt
- mannitol
Field of Science
- 2.5 Materials engineering
- 1.4 Chemical sciences
- 3.3 Health sciences
- 1.3 Physical sciences
Smart Specialization Area
- Smart materials, technology and engineering
Research output
- 3 Poster
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Changing MCC type (without composition change) to alter the mechanical properties of tablets obtained
Mohylyuk, V. (Corresponding Author), Kukuls, K., Frolova, A. J., Buczkowska, E. M. & Shmyrova, J., 1 Jun 2026. 1 p.Research output: Contribution to conference › Poster
Open Access -
Effect of microcrystalline cellulose (MCC) type and roll compaction force on the mechanical properties of tablets containing a high dose of poorly compactible substance
Mohylyuk, V. (Corresponding Author), Kukuls, K., Frolova, A. J., Buczkowska, E. M. & Shmyrova, J., 24 Mar 2026. 1 p.Research output: Contribution to conference › Poster › peer-review
Open Access -
Effect of diluent and binder type on the acetaminophen release from tablets under simulated fasted and fed conditions
Frolova, A. J., Gurkina, K., Kukuls, K. & Mohylyuk, V. (Corresponding Author), 24 Mar 2026. 1 p.Research output: Contribution to conference › Poster › peer-review
Open Access
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Investigation of the composition and preparation process variables on the tabletability and in vitro drug release: focus on the high drug-loaded formulations and poorly soluble drugs
Gurkina, K. (Project leader), Mohylyuk, V. (Supervisor) & Šitovs, A. (Supervisor)
2/02/26 → 2/02/31
Project: PhD projects
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Direct compression of highly used excipients in pharmaceutical tablet manufacturing: calcium phosphate dibasic anhydrous and microcrystalline cellulose
Kukuls, K. (Participant) & Mohylyuk, V. (Project leader)
1/08/23 → 31/07/27
Project: Projects outside RSU
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Suitability of sugar alcohols (polyols) as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties
Mohylyuk, V. (Project leader), Buczkowska, E. M. (Leading expert), Pētersone, L. (Leading expert), Žogota, M. (Expert), Horvath, Z. M. (Participant), Kukuls, K. (Participant) & Frolova, A. J. (Participant)
1/04/24 → 31/03/26
Project: Consolidation grants
Datasets
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Karl Fischer (KF) Titration of Polyols
Frolova, A. J. (Creator), Kukuls, K. (Creator), Horvath, Z. M. (Creator), Gniazdowska, E. M. (Creator), Pētersone, L. (Creator), Mohylyuk, V. (Creator) & Buczkowska, E. M. (Creator), Rīga Stradiņš University Institutional Repository Dataverse, 17 Mar 2025
DOI: 10.48510/fk2/4areio, https://doi.org/10.48510/FK2/4AREIO and one more link, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/4AREIO (show fewer)
Dataset
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Optical Microscopy of Polyols
Kukuls, K. (Creator), Frolova, A. J. (Creator), Horvath, Z. M. (Creator), Gniazdowska, E. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 22 Jan 2025
DOI: 10.48510/FK2/RBPONG, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/RBPONG
Dataset
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Intrinsic Dissolution Rate (IDR) of Polyols
Gniazdowska, E. M. (Creator), Frolova, A. J. (Creator), Kukuls, K. (Creator), Horvath, Z. M. (Creator) & Mohylyuk, V. (Creator), Riga Stradins University, 6 Feb 2025
DOI: 10.48510/FK2/BJPEC8, https://dataverse.rsu.lv/dataset.xhtml?persistentId=doi:10.48510/FK2/BJPEC8
Dataset
Press/Media
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Effect of diluent and binder type on the acetaminophen release from tablets under simulated fasted and fed conditions
Frolova, A. J., Gurkina, K., Kukuls, K. & Mohylyuk, V.
14/04/26
1 item of Media coverage
Press/Media