Epigenomic regulation of cancer immunity by dietary intervention

  • F. Fraga, Mario (Project leader)
  • Pjanova, Dace (Partner's coordinator)

Project Details

Description

The aim of the proposal is to unravel the epigenetic determinants mediating the immune effects of AID at the systemic level and at the tumor site, in patients with early stages of cancer. Primary aims: to analyse in the clinical setting AID-mediated modulation of immune cell profile and investigate the underlying epigenomic mechanisms in depth by sensitive and novel multi-omic approaches. Secondary aim: to identify and evaluate new epigenetic biomarkers and targets with translational potential.
AcronymDICE
StatusActive
Effective start/end date1/05/2430/04/27

Collaborative partners

  • Rīga Stradiņš University
  • Health Research Institute of Asturias (lead)
  • Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
  • The Rhodense Territorial Social Health Authority (ASST)
  • Hungarian Centre of Excellence for Molecular Medicine
  • Augsburg University

Keywords

  • Epigenomics
  • Multi-omics
  • Trained Immunity
  • Immunonutrition Diet
  • Neoplasms
  • Translational Research

Field of Science

  • 3.3 Health sciences

Smart Specialization Area

  • Biomedicine, medical technologies and biotechnology

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