Project Details
Description
Project aim (summary): It is well known that physical activity can prevent cancer development, but the molecular mechanisms behind these effects are poorly understood. During exercise, extracellular vesicles (EVs) are released into the circulation and mediate tissue crosstalk with potential effects on tumour cells and the immune tumour microenvironment. The overall aim of CancerBeat is to characterise the molecular cargo of exercise-induced EVs and explore their effects on breast cancer (BC) progression in vitro and in vivo.
| Short title | CancerBeat |
|---|---|
| Status | Finished |
| Effective start/end date | 1/05/21 → 30/04/24 |
| Links | https://biomed.lu.lv/project/eea-research-164/ |
Collaborative partners
- Rīga Stradiņš University
- Latvian Biomedical Research and Study Centre (lead)
- Oslo University Hospital
- National Cancer Institute, Lithuania
- National Institute of Chemical Physics and Biophysics, Tallinn
Keywords
- EV RNA cargo; EV protein cargo; cancer; exercise‐induced extracellular vesicles; muscle‐derived EVs; physical exercise.
Field of Science
- 3.3 Health sciences
Smart Specialization Area
- Social sciences and humanities as fields with horizontal impact on RIS3
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