System of rapid assessment of antibacterial resistance in patients with secondary bacterial infections

  • Lihacova, Ilze (Project leader)
  • Reinis, Aigars (Work package leader)
  • Jain, Nityanand (Assistant (student))
  • Bliznuks, Dmitrijs (Work package leader)
  • Lihachev, Alexey (Work package leader)
  • Ozoliņa, Liene (Administrative manager)

Project Details

Description

To develop and validate a novel, cost-effective prototype to reduce the time required for antimicrobial susceptibility test (AJT) evaluation. To realize this, the gold standard - disk diffusion - method and the laser speckle imaging technique will be combined, which will allow an early assessment of the diameter of the sterile zone. The proposed solution will significantly improve the effectiveness of antibacterial therapy for critically ill COVID-19 patients with bacterial infection and will contribute to the fight against the global problem - the growth of resistant bacterial strains. During the project, the proposed prototype device and AI-based algorithm will be tested in real-world conditions and tested in routine microbiology tests on various bacterial isolates and antimicrobial agents. The project team consists of biophotonics, electronics, information technology and microbiology experts, young scientists, master's and doctoral students from LU, RTU and experienced doctors from Paula Stradins Clinical University Hospital.

Layman's description

European Regional Development Fund (ERDF/ERAF)
StatusFinished
Effective start/end date1/01/2230/11/23

Keywords

  • Covid-19
  • antimicrobial susceptibility
  • disk diffusion
  • microbiology
  • infections

Field of Science

  • 3.3 Health sciences
  • 3.4 Medical biotechnology

Smart Specialization Area

  • Biomedicine, medical technologies and biotechnology

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.