Research output per year
Research output per year
Project Details
Description
Sestrins (SESNs), a family of evolutionarily conserved proteins, emerge as key physiological regulators in cellular adaptation to diverse stress stimuli. Scientific evidence highlights SESNs as potential biomarkers and significant regulators of muscle function in aging, therefore the aim of this study is: a) to provide reference of plasma SESN values in healthy young and older adults at baseline, during exercise, and in recovery in relation to their physical performance capacity; b) to investigate the systemic and muscle tissue-specific SESN-mediated metabolic adaptations to a polyphenol supplementation (PS), resistance training (RT) and their combined effect by performing comprehensive analysis of multiple factors involved.
| Acronym | EXPOSE |
|---|---|
| Status | Active |
| Effective start/end date | 1/04/24 → 31/03/26 |
Total Funding
- European Commission: €199,117.00
Keywords
- Aging
- muscle wasting
- sestrins
- resistance training
- polyphenol supplements
Field of Science
- 3.3 Health sciences
- 3.1 Basic medicine
Smart Specialization Area
- Biomedicine, medical technologies and biotechnology
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Effects of resistance-based training and polyphenol supplementation on physical function, metabolism, and inflammation in aging individuals
Flensted-Jensen, M. (Corresponding Author), Weinreich, C. M., Kleis-Olsen, A.-S., Hansen, F., Skyggelund, N. S., Pii, J. R., Whitlock, R., Abrahamsen, M.-L. B., Petersen, T. I., Karlsen, A., Reihmane, D. & Dela, F., 19 Aug 2025, (E-pub ahead of print) In: GeroScience.Research output: Contribution to journal › Article › peer-review
File3 Citations (Scopus)1 Downloads (Pure) -
Use of subjectively reported parameters of physical and mental fatigue, sleep and stress for assessment of ultra-endurance cycling induced cognitive impairment (Veloreality)
Lismane, D., Zolovs, M. & Reihmane, D., 1 Jul 2025, p. 57-57. 1 p.Research output: Contribution to conference › Abstract › peer-review
Open Access -
The Effect of Ultra Endurance Event on Cognitive Functions of Amateur Cyclists
Lismane, D., Reihmane, D. (Scientific Advisor) & Zolovs, M. (Scientific Advisor), 24 Mar 2025, p. 55-55.Research output: Contribution to conference › Abstract › peer-review
Open Access
Activities
- 1 Other expert activity
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Experts in the project "Systemic and muscle tissue-specific metabolic adaptations to EXercise and POlyphenol supplementation in aging: modulatory effects of SEstrins (EXPOSE)"
Pivovarova Ramich, O. (Expert ), Brownlee, I. (Expert ), Guadalupe-Grau, A. (Expert ), Flensted-Jensen, M. (Expert ), Dela, F. (Expert ), Vilne, B. (Expert ), Gailīte, L. (Expert ) & Gersone, G. (Expert )
1 Apr 2024 → 31 Mar 2026Activity: Expert activity types › Other expert activity