Возможность использования антиоксидантных ферментов эритроцитов в качестве индикаторов, характеризующих течение болезни у больных гемобластозами: Possibility of the use of erithrocyte antioxidative enzymes as indicators in characterization

Blood and erythrocytes of 50 healthy volunteers and 105 patiens with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients - remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidfant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and inctreased degree of ananemia.