Abstract
Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
| Translated title of the contribution | Possible use of erythrocyte antioxidant enzymes as markers of the course of disease in patients with hemoblastoses |
|---|---|
| Original language | Russian |
| Pages (from-to) | 144-147 |
| Number of pages | 4 |
| Journal | Voprosy Meditsinskoi Khimii |
| Volume | 42 |
| Issue number | 2 |
| Publication status | Published - Apr 1996 |
Field of Science*
- 3.1 Basic medicine
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database