Abstract
Neurofibromatosis type-1 (NF-1) -is a common genetic disease effecting the skin, subcutaneous tissue peripheral nerves and bones (tibia pseudarthrosis). Immunomodulatory viruses HHV-6 and HHV-7 are classibdng as a genus of roseoloviruses of subfamily fl-herpesviruses. Reactivation of HHV-6 and HHV-7 inhibits immune system and indirectly promote to other infectious agents. The article deals with a unique case repot of two repeated transplantations offibula due to congenital tibia pseudarthrosis caused by-NF-J. Results of the transplantations, related to active and latent HHV6 and HHV-7 infection in a 6 years old child are discussed in the paper.
| Translated title of the contribution | Outcomes of surgical correction of congenital tibia pseudarthrosis depending on the activation of HHV-6/HHV-7 viral infection in a child with neurofibromatosis type-1 |
|---|---|
| Original language | Russian |
| Pages (from-to) | 61-63 |
| Journal | Анестезиология и Pеаниматология = Anesteziologiya i Reanimatologiya |
| Issue number | 1 |
| Publication status | Published - 2014 |
Keywords*
- neurofibromatosis
- HHV-6
- HHV-7
- activeinfection
- latentinfection
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database