Эритремия: активность антиоксидантных ферментов эритроцитов, связь с дефицитом железа

V. I. Petukhov; A. O. Kumerova; A. G. Letse; A. A. Silova; M. A. Krishuna; Andrejs Šķesters; N. A. Mironova

Эритремия: активность антиоксидантных ферментов эритроцитов, связь с дефицитом железа

Translated title of the contribution: Erythremia: the activity of erythrocyte antioxidant enzymes and the association with iron deficiency

V. I. Petukhov
, A. O. Kumerova
, A. G. Letse
, A. A. Silova
, M. A. Krishuna
, Andrejs Šķesters
, N. A. Mironova

Rīga Stradiņš University

Research output: Contribution to journal › Article › peer-review

Abstract

Concentration of malonic dialdehyde (MDA) and activity of antioxidant enzymes G-6-PD, glutation peroxidase (GP), glutation reductase, catalase, superoxide dismutase were measured in red cells of patients with polycythemia vera. Plasmic ions Fe³⁺ were estimated by means of electron-paramagnetic resonance. MDA concentration and antioxidant enzymes (except GP) in polycythemia red cells were found increased, while the activity of selenium-dependent GP was reduced, the inhibition being greatest in severe iron deficiency. It is suggested that GP activity in red cells depends on both selenium levels in the body and concentrations of non-hematic iron.

Translated title of the contribution	Erythremia: the activity of erythrocyte antioxidant enzymes and the association with iron deficiency
Original language	Russian
Pages (from-to)	57-61
Journal	Terapevticheskii Arkhiv
Volume	69
Issue number	4
Publication status	Published - 1997

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Cite this

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title = "Эритремия: активность антиоксидантных ферментов эритроцитов, связь с дефицитом железа",

abstract = "Concentration of malonic dialdehyde (MDA) and activity of antioxidant enzymes G-6-PD, glutation peroxidase (GP), glutation reductase, catalase, superoxide dismutase were measured in red cells of patients with polycythemia vera. Plasmic ions Fe3+ were estimated by means of electron-paramagnetic resonance. MDA concentration and antioxidant enzymes (except GP) in polycythemia red cells were found increased, while the activity of selenium-dependent GP was reduced, the inhibition being greatest in severe iron deficiency. It is suggested that GP activity in red cells depends on both selenium levels in the body and concentrations of non-hematic iron.",

author = "Petukhov, \{V. I.\} and Kumerova, \{A. O.\} and Letse, \{A. G.\} and Silova, \{A. A.\} and Krishuna, \{M. A.\} and Andrejs {\v S}ķesters and Mironova, \{N. A.\}",

year = "1997",

language = "Russian",

volume = "69",

pages = "57--61",

journal = "Terapevticheskii Arkhiv",

issn = "0040-3660",

publisher = "Consilium MediCum",

number = "4",

}

TY - JOUR

T1 - Эритремия

T2 - активность антиоксидантных ферментов эритроцитов, связь с дефицитом железа

AU - Petukhov, V. I.

AU - Kumerova, A. O.

AU - Letse, A. G.

AU - Silova, A. A.

AU - Krishuna, M. A.

AU - Šķesters, Andrejs

AU - Mironova, N. A.

PY - 1997

Y1 - 1997

N2 - Concentration of malonic dialdehyde (MDA) and activity of antioxidant enzymes G-6-PD, glutation peroxidase (GP), glutation reductase, catalase, superoxide dismutase were measured in red cells of patients with polycythemia vera. Plasmic ions Fe3+ were estimated by means of electron-paramagnetic resonance. MDA concentration and antioxidant enzymes (except GP) in polycythemia red cells were found increased, while the activity of selenium-dependent GP was reduced, the inhibition being greatest in severe iron deficiency. It is suggested that GP activity in red cells depends on both selenium levels in the body and concentrations of non-hematic iron.

AB - Concentration of malonic dialdehyde (MDA) and activity of antioxidant enzymes G-6-PD, glutation peroxidase (GP), glutation reductase, catalase, superoxide dismutase were measured in red cells of patients with polycythemia vera. Plasmic ions Fe3+ were estimated by means of electron-paramagnetic resonance. MDA concentration and antioxidant enzymes (except GP) in polycythemia red cells were found increased, while the activity of selenium-dependent GP was reduced, the inhibition being greatest in severe iron deficiency. It is suggested that GP activity in red cells depends on both selenium levels in the body and concentrations of non-hematic iron.

UR - https://www.scopus.com/pages/publications/17744414290

UR - https://www-webofscience-com.db.rsu.lv/wos/woscc/full-record/WOS:A1997XC88000020

M3 - Article

C2 - 9213964

AN - SCOPUS:17744414290

SN - 0040-3660

VL - 69

SP - 57

EP - 61

JO - Terapevticheskii Arkhiv

JF - Terapevticheskii Arkhiv

IS - 4

ER -

Эритремия: активность антиоксидантных ферментов эритроцитов, связь с дефицитом железа

Abstract

UN SDGs

Field of Science*

Publication Type*

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