3-arylaziridine-2-carboxylic acid derivatives and (3-arylaziridin-2-yl)ketones: The aziridination approaches

Boriss Strumfs; Romans Uljanovs; Kirils Velikijs; Peteris Trapencieris; Ilze Strumfa

doi:10.3390/ijms22189861

3-arylaziridine-2-carboxylic acid derivatives and (3-arylaziridin-2-yl)ketones: The aziridination approaches

Boriss Strumfs, Romans Uljanovs, Kirils Velikijs, Peteris Trapencieris, Ilze Strumfa (Corresponding Author)

Department of Pathology

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

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Abstract

Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.

Original language	English
Article number	9861
Number of pages	28
Journal	International Journal of Molecular Sciences
Volume	22
Issue number	18
DOIs	https://doi.org/10.3390/ijms22189861
Publication status	Published - 13 Sept 2021

Keywords*

Aziridination
Aziridines
Carbenes
Imines
Nitrenes

Field of Science*

3.1 Basic medicine
1.4 Chemical sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.3390/ijms22189861Licence: CC BY

3-Arylaziridine-2-carboxylic AcidFinal published version, 17.3 MBLicence: CC BY

Cite this

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title = "3-arylaziridine-2-carboxylic acid derivatives and (3-arylaziridin-2-yl)ketones: The aziridination approaches",

abstract = "Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.",

keywords = "Aziridination, Aziridines, Carbenes, Imines, Nitrenes",

author = "Boriss Strumfs and Romans Uljanovs and Kirils Velikijs and Peteris Trapencieris and Ilze Strumfa",

note = "Funding Information: Funding: This research was funded by European Regional Development Fund; project number No. 1.1.1.2/VIAA/1/16/242. The APC was funded by Riga Stradins university, Riga, Latvia. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = sep,

day = "13",

doi = "10.3390/ijms22189861",

language = "English",

volume = "22",

journal = "International Journal of Molecular Sciences",

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T1 - 3-arylaziridine-2-carboxylic acid derivatives and (3-arylaziridin-2-yl)ketones

T2 - The aziridination approaches

AU - Strumfs, Boriss

AU - Uljanovs, Romans

AU - Velikijs, Kirils

AU - Trapencieris, Peteris

AU - Strumfa, Ilze

N1 - Funding Information: Funding: This research was funded by European Regional Development Fund; project number No. 1.1.1.2/VIAA/1/16/242. The APC was funded by Riga Stradins university, Riga, Latvia. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/9/13

Y1 - 2021/9/13

N2 - Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.

AB - Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.

KW - Aziridination

KW - Aziridines

KW - Carbenes

KW - Imines

KW - Nitrenes

UR - http://www.scopus.com/inward/record.url?scp=85114691230&partnerID=8YFLogxK

U2 - 10.3390/ijms22189861

DO - 10.3390/ijms22189861

M3 - Review article

C2 - 34576025

AN - SCOPUS:85114691230

SN - 1661-6596

VL - 22

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

IS - 18

M1 - 9861

ER -

3-arylaziridine-2-carboxylic acid derivatives and (3-arylaziridin-2-yl)ketones: The aziridination approaches

Abstract

Keywords*

Field of Science*

Publication Type*

Access to Document

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