3-arylaziridine-2-carboxylic acid derivatives and (3-arylaziridin-2-yl)ketones: The aziridination approaches

Boriss Strumfs, Romans Uljanovs, Kirils Velikijs, Peteris Trapencieris, Ilze Strumfa (Coresponding Author)

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)
6 Downloads (Pure)

Abstract

Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.

Original languageEnglish
Article number9861
Number of pages28
JournalInternational Journal of Molecular Sciences
Volume22
Issue number18
DOIs
Publication statusPublished - 13 Sep 2021

Keywords*

  • Aziridination
  • Aziridines
  • Carbenes
  • Imines
  • Nitrenes

Field of Science*

  • 3.1 Basic medicine
  • 1.4 Chemical sciences

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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