A case report of agressive adenocarcinoma of cervix with ovarian metastasis

Lāsma Tauriņa, Arta Spridzāne, Androniks Mitiļdžans

Research output: Contribution to conferenceAbstractpeer-review

Abstract

Cervical cancer is the fourth most common cancer in women worldwide. Cervical adenocarcinoma, as it was in this particular case, accounts approximately for 25 % of all invasive cervical cancers. Ovarian metastasis from cervical cancer is a rare phenomenon. Case report: A 28-year-old nulliparous woman was referred to LOC presenting with progressing lower abdomen discomfort and rapid abdominal enlargement. On her blood sample raised Carcinoembrional marker (CEA) was >2000 U/mL, CA125 - 233 U/mL were detected. Her abdominal CT scan revealed worrisome ovarian lesions and peritoneal dissemination suggesting of primary ovarian cancer. She did have a radical trachelectomy, parailiac bilateral lymphadenectomy 14 months ago due to stage IB1 (pT1b1NocMopL+V-G2Ro) usual type cervical adenocarcinoma. No adjuvant treatment was recommended according to Sedlis criteria on the multi disciplinary team meeting (MDT). Radical cytoreductive surgery, including total histerectomy, bilateral adnexectomy, rectum anterior resection, pelvic peritonectomy, infracolic omentectomy, right side cistoureteroneostomy and appendectomy was performed after confirming malignant lesions on frozen section histology. On the final histopathology report Grade 3 endocervical serous adenocarcinoma’s metastasis with mucinous differentiation (10%) were confirmed in all specimens. On the MDT combined chemotherapy including cisplatin, paclitaxel and bevacizumab was recommended.Keywords: Cervical adenocarcinoma, ovarian metastasis. This case study reports a presentation of complicated and rare medical situation, as well as facilitate a discussion about young oncological patients. This case report shows importance of accurate histology conclusion, allowing to make balanced decisions taking into account fertility desires and oncological outcomes.
Original languageEnglish
Pages79
Publication statusPublished - 24 Mar 2021
Externally publishedYes
EventRSU Research week 2021: Knowledge for Use in Practice - Rīga, Latvia
Duration: 24 Mar 202126 Mar 2021
https://rw2021.rsu.lv/conferences/knowledge-use-practice

Conference

ConferenceRSU Research week 2021: Knowledge for Use in Practice
Abbreviated titleRW2021
Country/TerritoryLatvia
CityRīga
Period24/03/2126/03/21
Internet address

Field of Science

  • 3.2 Clinical medicine

Publication Type

  • 3.4. Other publications in conference proceedings (including local)

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