A Comprehensive Case Report on Familial Multiple Lipomatosis

Fatima Ali Raza; Syed Abdullah Monawwer; Muhammad Husnain; Darja Golubeva; Laveeza Fatima; Md Ariful Haque

doi:10.1002/ccr3.9664

A Comprehensive Case Report on Familial Multiple Lipomatosis

Fatima Ali Raza, Syed Abdullah Monawwer, Muhammad Husnain, Darja Golubeva, Laveeza Fatima, Md Ariful Haque (Corresponding Author)

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Abstract

Familial multiple lipomatosis (FML) is a rare autosomal dominant disorder characterized by the progressive development of encapsulated nodules predominantly on the trunk and extremities. Its genetic basis is linked to HMGA-2 gene over-expression. The condition is diagnosed via clinical history, ultrasound findings, and histological studies, and management mainly comprises surgical excision. This case report highlights the clinical characteristics, diagnostic challenges, and management of FML in a38-year-old male.

Original language	English
Article number	e9664
Number of pages	4
Journal	Clinical Case Reports
Volume	12
Issue number	12
DOIs	https://doi.org/10.1002/ccr3.9664
Publication status	Published - Dec 2024
Externally published	Yes

Keywords*

Fml
HMGA-2 gene
Autosomal dominant disorder
Familial multiple lipomatosis

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

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10.1002/ccr3.9664Licence: CC BY

A Comprehensive Case Report on Familial Multiple LipomatosisFinal published version, 446 KBLicence: CC BY

Cite this

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AU - Fatima, Laveeza

AU - Haque, Md Ariful

PY - 2024/12

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AB - Familial multiple lipomatosis (FML) is a rare autosomal dominant disorder characterized by the progressive development of encapsulated nodules predominantly on the trunk and extremities. Its genetic basis is linked to HMGA-2 gene over-expression. The condition is diagnosed via clinical history, ultrasound findings, and histological studies, and management mainly comprises surgical excision. This case report highlights the clinical characteristics, diagnostic challenges, and management of FML in a38-year-old male.

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A Comprehensive Case Report on Familial Multiple Lipomatosis

Abstract

Keywords*

Field of Science*

Publication Type*

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