TY - JOUR
T1 - A Core Outcome Set for Pediatric Critical Care
AU - Fink, Ericka L.
AU - Maddux, Aline B.
AU - Pinto, Neethi
AU - Sorenson, Samuel
AU - Notterman, Daniel
AU - Dean, J. Michael
AU - Carcillo, Joseph A.
AU - Berg, Robert A.
AU - Zuppa, Athena
AU - Pollack, Murray M.
AU - Meert, Kathleen L.
AU - Hall, Mark W.
AU - Sapru, Anil
AU - McQuillen, Patrick S.
AU - Mourani, Peter M.
AU - Wessel, David
AU - Amey, Deborah
AU - Argent, Andrew
AU - Brunow de Carvalho, Werther
AU - Butt, Warwick
AU - Choong, Karen
AU - Curley, Martha A.Q.
AU - Del Pilar Arias Lopez, Maria
AU - Demirkol, Demet
AU - Grosskreuz, Ruth
AU - Houtrow, Amy J.
AU - Knoester, Hennie
AU - Lee, Jan Hau
AU - Long, Debbie
AU - Manning, Joseph C.
AU - Morrow, Brenda
AU - Sankar, Jhuma
AU - Slomine, Beth S.
AU - Smith, McKenna
AU - Olson, Lenora M.
AU - Watson, R. Scott
AU - Pediatric Outcomes STudies after PICU (POST-PICU) Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
AU - Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN)
A2 - Balmaks, Reinis
N1 - R.Balmaka vārds pie publikācijas nav minēts. Pēc autora sniegtās informācijas, viņš ir "Pediatric Outcomes STudies after PICU (POST-PICU) Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network" darba grupas sastāvā.
Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2020/12/1
Y1 - 2020/12/1
N2 - OBJECTIVES: More children are surviving critical illness but are at risk of residual or new health conditions. An evidence-informed and stakeholder-recommended core outcome set is lacking for pediatric critical care outcomes. Our objective was to create a multinational, multistakeholder-recommended pediatric critical care core outcome set for inclusion in clinical and research programs. DESIGN: A two-round modified Delphi electronic survey was conducted with 333 invited research, clinical, and family/advocate stakeholders. Stakeholders completing the first round were invited to participate in the second. Outcomes scoring greater than 69% "critical" and less than 15% "not important" advanced to round 2 with write-in outcomes considered. The Steering Committee held a virtual consensus conference to determine the final components. SETTING: Multinational survey. PATIENTS: Stakeholder participants from six continents representing clinicians, researchers, and family/advocates. MEASUREMENTS AND MAIN RESULTS: Overall response rates were 75% and 82% for each round. Participants voted on seven Global Domains and 45 Specific Outcomes in round 1, and six Global Domains and 30 Specific Outcomes in round 2. Using overall (three stakeholder groups combined) results, consensus was defined as outcomes scoring greater than 90% "critical" and less than 15% "not important" and were included in the final PICU core outcome set: four Global Domains (Cognitive, Emotional, Physical, and Overall Health) and four Specific Outcomes (Child Health-Related Quality of Life, Pain, Survival, and Communication). Families (n = 21) suggested additional critically important outcomes that did not meet consensus, which were included in the PICU core outcome set-extended. CONCLUSIONS: The PICU core outcome set and PICU core outcome set-extended are multistakeholder-recommended resources for clinical and research programs that seek to improve outcomes for children with critical illness and their families.
AB - OBJECTIVES: More children are surviving critical illness but are at risk of residual or new health conditions. An evidence-informed and stakeholder-recommended core outcome set is lacking for pediatric critical care outcomes. Our objective was to create a multinational, multistakeholder-recommended pediatric critical care core outcome set for inclusion in clinical and research programs. DESIGN: A two-round modified Delphi electronic survey was conducted with 333 invited research, clinical, and family/advocate stakeholders. Stakeholders completing the first round were invited to participate in the second. Outcomes scoring greater than 69% "critical" and less than 15% "not important" advanced to round 2 with write-in outcomes considered. The Steering Committee held a virtual consensus conference to determine the final components. SETTING: Multinational survey. PATIENTS: Stakeholder participants from six continents representing clinicians, researchers, and family/advocates. MEASUREMENTS AND MAIN RESULTS: Overall response rates were 75% and 82% for each round. Participants voted on seven Global Domains and 45 Specific Outcomes in round 1, and six Global Domains and 30 Specific Outcomes in round 2. Using overall (three stakeholder groups combined) results, consensus was defined as outcomes scoring greater than 90% "critical" and less than 15% "not important" and were included in the final PICU core outcome set: four Global Domains (Cognitive, Emotional, Physical, and Overall Health) and four Specific Outcomes (Child Health-Related Quality of Life, Pain, Survival, and Communication). Families (n = 21) suggested additional critically important outcomes that did not meet consensus, which were included in the PICU core outcome set-extended. CONCLUSIONS: The PICU core outcome set and PICU core outcome set-extended are multistakeholder-recommended resources for clinical and research programs that seek to improve outcomes for children with critical illness and their families.
UR - http://www.scopus.com/inward/record.url?scp=85097004323&partnerID=8YFLogxK
U2 - 10.1097/CCM.0000000000004660
DO - 10.1097/CCM.0000000000004660
M3 - Article
C2 - 33048905
AN - SCOPUS:85097004323
SN - 0090-3493
VL - 48
SP - 1819
EP - 1828
JO - Critical Care Medicine
JF - Critical Care Medicine
IS - 12
ER -