A cross-sectional survey of urinary iodine status in Latvia

Ilze Konrade, Lolita Neimane, Marina Makrecka, Ieva Strele, Edgars Liepinsh, Aivars Lejnieks, Parsla Vevere, Ugis Gruntmanis, Valdis Pirags, Maija Dambrova

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Background and objective: A nationwide survey of schoolchildren was conducted to detect regional differences in urinary iodine excretion in Latvia and to compare the results with data from the newborn thyroid-stimulating hormone (TSH) screening database as well with the results of a similar study performed in Latvia 10 years ago. Materials and methods: We conducted a cross-sectional school-based cluster survey of 915 children aged 9-12 years in 46 randomly selected schools in all regions of Latvia. Urine samples, questionnaires on the consumption of iodized salt and information on socioeconomic status were collected. TSH levels in newborns were also measured. Results: The median creatinine-standardized urinary iodine concentration (UIC) in our study was 107.3 mg/g Cr. UIC measurements indicative of mild iodine deficiency were present in 31.6%, moderate deficiency in 11.9% and severe deficiency in 2.8% of the participants. The prevalence of iodine deficiency was the highest in the southeastern region of Latgale and the northeastern region of Vidzeme. The prevalence of TSH values >5 mIU/L followed a similar pattern. The self-reported prevalence of regular iodized salt consumption was 10.2%. Children from urban schools had a significantly lower UIC than children from rural schools. Conclusions: Our findings suggest that although the overall median UIC in Latvian schoolchildren falls within the lower normal range, almost 50% of the schoolchildren are iodine deficient, especially in urban schools and in the eastern part of Latvia. The absence of amandatory salt iodization program puts a significant number of children and pregnantwomen at risk.

Original languageEnglish
Pages (from-to)124-129
Number of pages6
JournalMedicina (Lithuania)
Volume50
Issue number2
DOIs
Publication statusPublished - 2014

Keywords

  • Deficiency
  • Iodine
  • Iodized salt
  • Thyroid stimulating hormone

Field of Science

  • 3.1 Basic medicine
  • 3.2 Clinical medicine
  • 3.3 Health sciences

Publication Type

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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