A multicenter, double-blind, parallel group, placebo-controlled clinical study to examine the safety and efficacy of T-clair SPHP700-3 in the management of mild to moderate dry eye in adults

Edoardo Villani, Guna Laganovska, Francesco Viola, Cesare Pirondini, Kristine Baumane, Liga Radecka, Roberto Ratiglia

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Purpose: To study the safety and efficacy of T-Clair SPHP700-3, a new over-the-counter preservative-free formulation, in the management of mild to moderate dry eye in adults. Methods: Sixty adult patients with mild to moderate dry eye were consecutively recruited in 2 eye clinics and randomized into 2 groups: treatment and placebo. Signs and symptoms of dry eye were compared along 28 days of treatment. Results: No adverse events were reported during the study. Symptoms and signs of dry eye showed significant differences between the 2 groups after 2 and 4 weeks of treatment. Conclusions: SPHP700-3 preservative-free formulation showed to be safe and effective in mild to moderate dry eye, improving tear film stability, ocular surface lubrification, and patients' symptomatology.

Original languageEnglish
Pages (from-to)265-268
Number of pages4
JournalCornea
Volume30
Issue number3
DOIs
Publication statusPublished - Mar 2011
Externally publishedYes

Keywords*

  • dry eye
  • ocular surface
  • over-the-counter eyedrops
  • preservative-free formulation

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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