A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES

Vladimirs Kozlovs; Mihails Bariševs; Dmitrijs Merkulovs; Šimons Svirskis

A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES

Vladimirs Kozlovs (Corresponding Author)
, Mihails Bariševs
, Dmitrijs Merkulovs (Corresponding Author)
, Šimons Svirskis

Institute of Microbiology and Virology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

Abstract

We present the design and operating principles of a novel differential refractometer optimized for high resolution analysis of binary liquid mixtures.
Experimental evaluation demonstrated a refractive index resolution of 5.10−7 nD. Notably, the method shows low sensitivity to minor temperature fluctuations, making it especially suitable for the analysis of low-concentration aqueous dispersions of polymer nanoparticles, where ultra-high resolution (better than
1.10−5 nD) and stable temperature control are essential.

Original language	English
Title of host publication	Medical Physics in the Baltic States
Subtitle of host publication	Proceedings of the 17th International Conference on Medical Physics
Editors	Diana Adliene
Place of Publication	Kaunas
Publisher	Kaunas University of Technology
Pages	112-114
Number of pages	3
Publication status	Published - 6 Nov 2025
Event	The 17th International Conference on Medical Physics - Kaunas, Lithuania Duration: 6 Nov 2025 → 8 Nov 2025

Publication series

Name	Medical Physics in the Baltic States
Volume	17
ISSN (Electronic)	1822-5721

Conference

Conference	The 17th International Conference on Medical Physics
Country/Territory	Lithuania
City	Kaunas
Period	6/11/25 → 8/11/25

Field of Science*

3.1 Basic medicine

Publication Type*

3.2. Articles or chapters in other proceedings other than those included in 3.1., with an ISBN or ISSN code

Access to Document

A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISIONFinal published version, 535 KBLicence: CC BY-NC-ND

https://medphys.lt/medphys2025/index.php/proceedings-of-the-conferenceLicence: CC BY-NC-ND

Cite this

Kozlovs, V., Bariševs, M., Merkulovs, D., & Svirskis, Š. (2025). A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES. In D. Adliene (Ed.), Medical Physics in the Baltic States: Proceedings of the 17th International Conference on Medical Physics (pp. 112-114). (Medical Physics in the Baltic States; Vol. 17). Kaunas University of Technology. https://medphys.lt/medphys2025/index.php/proceedings-of-the-conference

Kozlovs, Vladimirs ; Bariševs, Mihails ; Merkulovs, Dmitrijs et al. / A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES. Medical Physics in the Baltic States: Proceedings of the 17th International Conference on Medical Physics. editor / Diana Adliene. Kaunas : Kaunas University of Technology, 2025. pp. 112-114 (Medical Physics in the Baltic States).

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title = "A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES",

abstract = "We present the design and operating principles of a novel differential refractometer optimized for high resolution analysis of binary liquid mixtures. Experimental evaluation demonstrated a refractive index resolution of 5.10−7 nD. Notably, the method shows low sensitivity to minor temperature fluctuations, making it especially suitable for the analysis of low-concentration aqueous dispersions of polymer nanoparticles, where ultra-high resolution (better than 1.10−5 nD) and stable temperature control are essential. ",

author = "Vladimirs Kozlovs and Mihails Bari{\v s}evs and Dmitrijs Merkulovs and {\v S}imons Svirskis",

note = "Konferences tē{\v z}u grāmata: https://medphys.lt/medphys2025/images/Medphys25/Proceedings\%20book.pdf; The 17th International Conference on Medical Physics ; Conference date: 06-11-2025 Through 08-11-2025",

year = "2025",

month = nov,

day = "6",

language = "English",

series = "Medical Physics in the Baltic States",

publisher = "Kaunas University of Technology",

pages = "112--114",

editor = "Diana Adliene",

booktitle = "Medical Physics in the Baltic States",

address = "Lithuania",

}

Kozlovs, V , Bariševs, M, Merkulovs, D & Svirskis, Š 2025, A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES. in D Adliene (ed.), Medical Physics in the Baltic States: Proceedings of the 17th International Conference on Medical Physics. Medical Physics in the Baltic States, vol. 17, Kaunas University of Technology, Kaunas, pp. 112-114, The 17th International Conference on Medical Physics, Kaunas, Lithuania, 6/11/25. <https://medphys.lt/medphys2025/index.php/proceedings-of-the-conference>

A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES. / Kozlovs, Vladimirs (Corresponding Author); Bariševs, Mihails; Merkulovs, Dmitrijs (Corresponding Author) et al.
Medical Physics in the Baltic States: Proceedings of the 17th International Conference on Medical Physics. ed. / Diana Adliene. Kaunas: Kaunas University of Technology, 2025. p. 112-114 (Medical Physics in the Baltic States; Vol. 17).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

TY - GEN

T1 - A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES

AU - Kozlovs, Vladimirs

AU - Bariševs, Mihails

AU - Merkulovs, Dmitrijs

AU - Svirskis, Šimons

N1 - Konferences tēžu grāmata: https://medphys.lt/medphys2025/images/Medphys25/Proceedings%20book.pdf

PY - 2025/11/6

Y1 - 2025/11/6

N2 - We present the design and operating principles of a novel differential refractometer optimized for high resolution analysis of binary liquid mixtures. Experimental evaluation demonstrated a refractive index resolution of 5.10−7 nD. Notably, the method shows low sensitivity to minor temperature fluctuations, making it especially suitable for the analysis of low-concentration aqueous dispersions of polymer nanoparticles, where ultra-high resolution (better than 1.10−5 nD) and stable temperature control are essential.

AB - We present the design and operating principles of a novel differential refractometer optimized for high resolution analysis of binary liquid mixtures. Experimental evaluation demonstrated a refractive index resolution of 5.10−7 nD. Notably, the method shows low sensitivity to minor temperature fluctuations, making it especially suitable for the analysis of low-concentration aqueous dispersions of polymer nanoparticles, where ultra-high resolution (better than 1.10−5 nD) and stable temperature control are essential.

M3 - Conference contribution

T3 - Medical Physics in the Baltic States

SP - 112

EP - 114

BT - Medical Physics in the Baltic States

A2 - Adliene, Diana

PB - Kaunas University of Technology

CY - Kaunas

T2 - The 17th International Conference on Medical Physics

Y2 - 6 November 2025 through 8 November 2025

ER -

A NOVEL DIFFERENTIAL REFRACTOMETER FOR HIGH-PRECISION ANALYSIS OF BINARY LIQUID MIXTURES

Abstract

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