Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?

Djordje S. Popovic; Dimitrios Patoulias; Theocharis Koufakis; Konstantinos Stavropoulos; Paschalis Karakasis; Ieva Ruža; Nikolaos Papanas; Manfredi Rizzo; Michael Doumas

doi:10.1016/j.jdiacomp.2024.108800

Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?

Djordje S. Popovic (Corresponding Author), Dimitrios Patoulias, Theocharis Koufakis, Konstantinos Stavropoulos, Paschalis Karakasis, Ieva Ruža, Nikolaos Papanas, Manfredi Rizzo, Michael Doumas

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.

Original language	English
Article number	108800
Journal	Journal of Diabetes and its Complications
Volume	38
Issue number	8
DOIs	https://doi.org/10.1016/j.jdiacomp.2024.108800
Publication status	Published - Aug 2024
Externally published	Yes

Keywords*

Normoglycemia
Tirzepatide
Type 2 diabetes

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jdiacomp.2024.108800

Cite this

Popovic, D. S., Patoulias, D., Koufakis, T., Stavropoulos, K., Karakasis, P., Ruža, I., Papanas, N., Rizzo, M., & Doumas, M. (2024). Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission? Journal of Diabetes and its Complications, 38(8), Article 108800. https://doi.org/10.1016/j.jdiacomp.2024.108800

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abstract = "We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.",

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year = "2024",

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doi = "10.1016/j.jdiacomp.2024.108800",

language = "English",

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T1 - Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus

T2 - A step closer to drug-induced diabetes remission?

AU - Popovic, Djordje S.

AU - Patoulias, Dimitrios

AU - Koufakis, Theocharis

AU - Stavropoulos, Konstantinos

AU - Karakasis, Paschalis

AU - Ruža, Ieva

AU - Papanas, Nikolaos

AU - Rizzo, Manfredi

AU - Doumas, Michael

PY - 2024/8

Y1 - 2024/8

N2 - We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.

AB - We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.

KW - Normoglycemia

KW - Tirzepatide

KW - Type 2 diabetes

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U2 - 10.1016/j.jdiacomp.2024.108800

DO - 10.1016/j.jdiacomp.2024.108800

M3 - Article

C2 - 38889536

AN - SCOPUS:85196153360

SN - 1056-8727

VL - 38

JO - Journal of Diabetes and its Complications

JF - Journal of Diabetes and its Complications

IS - 8

M1 - 108800

ER -

Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?

Abstract

Keywords*

Field of Science*

Publication Type*

UN SDGs

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