Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?

Djordje S. Popovic; Dimitrios Patoulias; Theocharis Koufakis; Konstantinos Stavropoulos; Paschalis Karakasis; Ieva Ruža; Nikolaos Papanas; Manfredi Rizzo; Michael Doumas

doi:10.1016/j.jdiacomp.2024.108800

Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?

Djordje S. Popovic^* (Corresponding Author)
, Dimitrios Patoulias
, Theocharis Koufakis
, Konstantinos Stavropoulos
, Paschalis Karakasis
, Ieva Ruža
, Nikolaos Papanas
, Manfredi Rizzo
, Michael Doumas

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.

Original language	English
Article number	108800
Journal	Journal of Diabetes and its Complications
Volume	38
Issue number	8
DOIs	https://doi.org/10.1016/j.jdiacomp.2024.108800
Publication status	Published - Aug 2024
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords*

Normoglycemia
Tirzepatide
Type 2 diabetes

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.1016/j.jdiacomp.2024.108800

Cite this

Popovic, D. S., Patoulias, D., Koufakis, T., Stavropoulos, K., Karakasis, P., Ruža, I., Papanas, N., Rizzo, M., & Doumas, M. (2024). Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission? Journal of Diabetes and its Complications, 38(8), Article 108800. https://doi.org/10.1016/j.jdiacomp.2024.108800

@article{844450c0d69149739230faa28564d976,

title = "Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?",

abstract = "We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 \%. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.",

keywords = "Normoglycemia, Tirzepatide, Type 2 diabetes",

author = "Popovic, \{Djordje S.\} and Dimitrios Patoulias and Theocharis Koufakis and Konstantinos Stavropoulos and Paschalis Karakasis and Ieva Ru{\v z}a and Nikolaos Papanas and Manfredi Rizzo and Michael Doumas",

note = "Publisher Copyright: {\textcopyright} 2024 Elsevier Inc.",

year = "2024",

month = aug,

doi = "10.1016/j.jdiacomp.2024.108800",

language = "English",

volume = "38",

journal = "Journal of Diabetes and its Complications",

issn = "1056-8727",

publisher = "Elsevier Inc.",

number = "8",

}

TY - JOUR

T1 - Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus

T2 - A step closer to drug-induced diabetes remission?

AU - Popovic, Djordje S.

AU - Patoulias, Dimitrios

AU - Koufakis, Theocharis

AU - Stavropoulos, Konstantinos

AU - Karakasis, Paschalis

AU - Ruža, Ieva

AU - Papanas, Nikolaos

AU - Rizzo, Manfredi

AU - Doumas, Michael

PY - 2024/8

Y1 - 2024/8

N2 - We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.

AB - We sought to determine whether treatment with tirzepatide in type 2 diabetes mellitus (T2DM) patients can increase the odds for achieving normoglycemia, compatible with glycated hemoglobin levels lower than 5.7 %. We demonstrated that treatment with tirzepatide versus control increased the odds for achievement of normoglycemia by >16 times.

KW - Normoglycemia

KW - Tirzepatide

KW - Type 2 diabetes

UR - https://www.scopus.com/pages/publications/85196153360

U2 - 10.1016/j.jdiacomp.2024.108800

DO - 10.1016/j.jdiacomp.2024.108800

M3 - Article

C2 - 38889536

AN - SCOPUS:85196153360

SN - 1056-8727

VL - 38

JO - Journal of Diabetes and its Complications

JF - Journal of Diabetes and its Complications

IS - 8

M1 - 108800

ER -

Achievement of normoglycemia with tirzepatide in type 2 diabetes mellitus: A step closer to drug-induced diabetes remission?

Abstract

UN SDGs

Keywords*

Field of Science*

Publication Type*

Access to Document

Other files and links

Fingerprint

Cite this