Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe

B. Bozdogan; P. C. Appelbaum; L. M. Kelly; D. B. Hoellman; A. Tambic-Andrasevic; L. Drukalska; W. Hryniewicz; H. Hupkova; M. R. Jacobs; J. Kolman; M. Konkoly-Thege; J. Miciuleviciene; M. Pana; L. Setchanova; J. Trupl; P. Urbaskova

doi:10.1046/j.1469-0691.2003.00598.x

Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe

B. Bozdogan, P. C. Appelbaum, L. M. Kelly, D. B. Hoellman, A. Tambic-Andrasevic, L. Drukalska, W. Hryniewicz, H. Hupkova, M. R. Jacobs, J. Kolman, M. Konkoly-Thege, J. Miciuleviciene, M. Pana, L. Setchanova, J. Trupl, P. Urbaskova

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

In total, 1039 pediatric Streptococcus pyogenes isolates from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia and Slovenia were studied. All strains were susceptible to penicillin G, levofloxacin, and quinupristin-dalfopristin, 91-100% to telithromycin, and 82-100% to erythromycin, azithromycin, and clarithromycin, and 90-100% to clindamycin. Macrolide resistance occurred mainly in Slovakia (25%), the Czech Republic (17.3%), and Croatia (15.8%). Overall, 9.7% of S. pyogenes isolates were erythromycin resistant due to erm(B)- or erm(A)-encoded methylases (72.3%) or to a mef(A)-encoded efflux pump (25.7%). One strain had alterations of both 23S rRNA (A2058G Escherichia coli numbering) and ribosomal protein L22 (G95D).

Original language	English
Pages (from-to)	741-745
Number of pages	5
Journal	Clinical Microbiology and Infection
Volume	9
Issue number	7
DOIs	https://doi.org/10.1046/j.1469-0691.2003.00598.x
Publication status	Published - 1 Jul 2003
Externally published	Yes

Keywords*

Macrolide resistance
Streptococcus pyogenes
Telithromycin

Field of Science*

3.1 Basic medicine
3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1046/j.1469-0691.2003.00598.x

https://www-sciencedirect-com.db.rsu.lv/science/article/pii/S1198743X14639720

Cite this

Bozdogan, B., Appelbaum, P. C., Kelly, L. M., Hoellman, D. B., Tambic-Andrasevic, A., Drukalska, L., Hryniewicz, W., Hupkova, H., Jacobs, M. R., Kolman, J., Konkoly-Thege, M., Miciuleviciene, J., Pana, M., Setchanova, L., Trupl, J., & Urbaskova, P. (2003). Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe. Clinical Microbiology and Infection, 9(7), 741-745. https://doi.org/10.1046/j.1469-0691.2003.00598.x

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abstract = "In total, 1039 pediatric Streptococcus pyogenes isolates from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia and Slovenia were studied. All strains were susceptible to penicillin G, levofloxacin, and quinupristin-dalfopristin, 91-100% to telithromycin, and 82-100% to erythromycin, azithromycin, and clarithromycin, and 90-100% to clindamycin. Macrolide resistance occurred mainly in Slovakia (25%), the Czech Republic (17.3%), and Croatia (15.8%). Overall, 9.7% of S. pyogenes isolates were erythromycin resistant due to erm(B)- or erm(A)-encoded methylases (72.3%) or to a mef(A)-encoded efflux pump (25.7%). One strain had alterations of both 23S rRNA (A2058G Escherichia coli numbering) and ribosomal protein L22 (G95D).",

keywords = "Macrolide resistance, Streptococcus pyogenes, Telithromycin",

author = "B. Bozdogan and Appelbaum, {P. C.} and Kelly, {L. M.} and Hoellman, {D. B.} and A. Tambic-Andrasevic and L. Drukalska and W. Hryniewicz and H. Hupkova and Jacobs, {M. R.} and J. Kolman and M. Konkoly-Thege and J. Miciuleviciene and M. Pana and L. Setchanova and J. Trupl and P. Urbaskova",

year = "2003",

month = jul,

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doi = "10.1046/j.1469-0691.2003.00598.x",

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Bozdogan, B, Appelbaum, PC, Kelly, LM, Hoellman, DB, Tambic-Andrasevic, A, Drukalska, L, Hryniewicz, W, Hupkova, H, Jacobs, MR, Kolman, J, Konkoly-Thege, M, Miciuleviciene, J, Pana, M, Setchanova, L, Trupl, J & Urbaskova, P 2003, 'Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe', Clinical Microbiology and Infection, vol. 9, no. 7, pp. 741-745. https://doi.org/10.1046/j.1469-0691.2003.00598.x

TY - JOUR

T1 - Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe

AU - Bozdogan, B.

AU - Appelbaum, P. C.

AU - Kelly, L. M.

AU - Hoellman, D. B.

AU - Tambic-Andrasevic, A.

AU - Drukalska, L.

AU - Hryniewicz, W.

AU - Hupkova, H.

AU - Jacobs, M. R.

AU - Kolman, J.

AU - Konkoly-Thege, M.

AU - Miciuleviciene, J.

AU - Pana, M.

AU - Setchanova, L.

AU - Trupl, J.

AU - Urbaskova, P.

PY - 2003/7/1

Y1 - 2003/7/1

N2 - In total, 1039 pediatric Streptococcus pyogenes isolates from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia and Slovenia were studied. All strains were susceptible to penicillin G, levofloxacin, and quinupristin-dalfopristin, 91-100% to telithromycin, and 82-100% to erythromycin, azithromycin, and clarithromycin, and 90-100% to clindamycin. Macrolide resistance occurred mainly in Slovakia (25%), the Czech Republic (17.3%), and Croatia (15.8%). Overall, 9.7% of S. pyogenes isolates were erythromycin resistant due to erm(B)- or erm(A)-encoded methylases (72.3%) or to a mef(A)-encoded efflux pump (25.7%). One strain had alterations of both 23S rRNA (A2058G Escherichia coli numbering) and ribosomal protein L22 (G95D).

AB - In total, 1039 pediatric Streptococcus pyogenes isolates from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia and Slovenia were studied. All strains were susceptible to penicillin G, levofloxacin, and quinupristin-dalfopristin, 91-100% to telithromycin, and 82-100% to erythromycin, azithromycin, and clarithromycin, and 90-100% to clindamycin. Macrolide resistance occurred mainly in Slovakia (25%), the Czech Republic (17.3%), and Croatia (15.8%). Overall, 9.7% of S. pyogenes isolates were erythromycin resistant due to erm(B)- or erm(A)-encoded methylases (72.3%) or to a mef(A)-encoded efflux pump (25.7%). One strain had alterations of both 23S rRNA (A2058G Escherichia coli numbering) and ribosomal protein L22 (G95D).

KW - Macrolide resistance

KW - Streptococcus pyogenes

KW - Telithromycin

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U2 - 10.1046/j.1469-0691.2003.00598.x

DO - 10.1046/j.1469-0691.2003.00598.x

M3 - Article

C2 - 12925122

AN - SCOPUS:0042026411

SN - 1198-743X

VL - 9

SP - 741

EP - 745

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 7

ER -

Activity of telithromycin compared with seven other agents against 1039 Streptococcus pyogenes pediatric isolates from ten centers in central and eastern Europe

Abstract

Keywords*

Field of Science*

Publication Type*

UN SDGs

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