Abstract
Oral lichen planus (OLP) is a common mucocutaneous disorder affecting approximately 1–2% of
the population, predominantly middle-aged women. This study aims to analyse the demographic
and clinical characteristics of OLP patients treated at the Oral Medicine Centre of Institute of Stomatology, Rīga Stradiņš University. The cohort comprised adult patients diagnosed with OLP,
who underwent structured clinical evaluations. The study identified significant patterns in age,
gender distribution, clinical forms, and associated discomfort levels. Females constituted 75.76%
of the cohort, with a mean age of 60 years. The reticular form of OLP was most prevalent, while
the erosive form, associated with considerable discomfort, was more common in females. Treatment regimens varied, with Sol Kenalog 0.2% and Ointment Clobetasol 0.05% being the primary therapies. Sol Kenalog 0.2% was more effective in providing symptom relief and reducing relapse frequency. Chronic diseases and stress were prevalent among patients, complicating management and treatment outcomes. The study emphasises the need for personalised treatment strategies that consider the severity of the clinical form, patient comfort, and comorbid conditions.
Further research is recommended to validate these findings and explore the underlying mechanisms of gender differences and the impact of comorbidities on OLP. The insights from this study aim to enhance clinical practices and improve patient outcomes.
the population, predominantly middle-aged women. This study aims to analyse the demographic
and clinical characteristics of OLP patients treated at the Oral Medicine Centre of Institute of Stomatology, Rīga Stradiņš University. The cohort comprised adult patients diagnosed with OLP,
who underwent structured clinical evaluations. The study identified significant patterns in age,
gender distribution, clinical forms, and associated discomfort levels. Females constituted 75.76%
of the cohort, with a mean age of 60 years. The reticular form of OLP was most prevalent, while
the erosive form, associated with considerable discomfort, was more common in females. Treatment regimens varied, with Sol Kenalog 0.2% and Ointment Clobetasol 0.05% being the primary therapies. Sol Kenalog 0.2% was more effective in providing symptom relief and reducing relapse frequency. Chronic diseases and stress were prevalent among patients, complicating management and treatment outcomes. The study emphasises the need for personalised treatment strategies that consider the severity of the clinical form, patient comfort, and comorbid conditions.
Further research is recommended to validate these findings and explore the underlying mechanisms of gender differences and the impact of comorbidities on OLP. The insights from this study aim to enhance clinical practices and improve patient outcomes.
| Original language | English |
|---|---|
| Pages (from-to) | 303-310 |
| Number of pages | 8 |
| Journal | Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences |
| Volume | 78 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Sept 2024 |
Keywords*
- clinical evaluations
- treatment effectiveness
- stress
- chronic conditions
Field of Science*
- 3.1 Basic medicine
- 3.2 Clinical medicine
Publication Type*
- 1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions)