Autofluorescence imaging for recurrence detection in skin cancer postoperative scars

Mindaugas Tamošiūnas; Emilija V. Plorina; Marta Lange; Aleksandrs Derjabo; Ilona Kuzmina; Dmitrijs Bļizņuks; Janis Spigulis

doi:10.1002/jbio.201900162

Autofluorescence imaging for recurrence detection in skin cancer postoperative scars

Mindaugas Tamošiūnas (Corresponding Author), Emilija V. Plorina, Marta Lange, Aleksandrs Derjabo, Ilona Kuzmina, Dmitrijs Bļizņuks, Janis Spigulis

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

This clinical study is a first attempt to use autofluorescence for recurrence diagnosis of skin cancer in postoperative scars. The proposed diagnostic parameter is based on a reduction in scar autofluorescence, evaluated in the green spectral channel. The validity of the method has been tested on 110 postoperative scars from 56 patients suspected of non-melanoma skin cancer, with eight patients (13 scars) available for the repeated examination. The recurrence diagnosis within a scar has been made after two subsequent autofluorescence check-ups, representing the temporal difference between the scar autofluorescence amplitudes as a vector. The recognition of recurrence has been discussed to represent the significant deviations from the value of vector angle θ. This new autofluorescence-based method can be easily integrated into the postoperative monitoring of surgical scars and can help diagnose the recurrence of skin cancer from the early stage of scar development.

Original language	English
Article number	e201900162
Pages (from-to)	e201900162
Journal	Journal of Biophotonics
Volume	13
Issue number	3
DOIs	https://doi.org/10.1002/jbio.201900162
Publication status	Published - 1 Mar 2020
Externally published	Yes

Keywords*

autofluorescence imaging
recurrence
scar
skin cancer
surgery

Field of Science*

3.2 Clinical medicine
1.3 Physical sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jbio.201900162

Cite this

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title = "Autofluorescence imaging for recurrence detection in skin cancer postoperative scars",

abstract = "This clinical study is a first attempt to use autofluorescence for recurrence diagnosis of skin cancer in postoperative scars. The proposed diagnostic parameter is based on a reduction in scar autofluorescence, evaluated in the green spectral channel. The validity of the method has been tested on 110 postoperative scars from 56 patients suspected of non-melanoma skin cancer, with eight patients (13 scars) available for the repeated examination. The recurrence diagnosis within a scar has been made after two subsequent autofluorescence check-ups, representing the temporal difference between the scar autofluorescence amplitudes as a vector. The recognition of recurrence has been discussed to represent the significant deviations from the value of vector angle θ. This new autofluorescence-based method can be easily integrated into the postoperative monitoring of surgical scars and can help diagnose the recurrence of skin cancer from the early stage of scar development.",

keywords = "autofluorescence imaging, recurrence, scar, skin cancer, surgery",

author = "Mindaugas Tamo{\v s}iūnas and Plorina, {Emilija V.} and Marta Lange and Aleksandrs Derjabo and Ilona Kuzmina and Dmitrijs Bļizņuks and Janis Spigulis",

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doi = "10.1002/jbio.201900162",

language = "English",

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TY - JOUR

T1 - Autofluorescence imaging for recurrence detection in skin cancer postoperative scars

AU - Tamošiūnas, Mindaugas

AU - Plorina, Emilija V.

AU - Lange, Marta

AU - Derjabo, Aleksandrs

AU - Kuzmina, Ilona

AU - Bļizņuks, Dmitrijs

AU - Spigulis, Janis

PY - 2020/3/1

Y1 - 2020/3/1

N2 - This clinical study is a first attempt to use autofluorescence for recurrence diagnosis of skin cancer in postoperative scars. The proposed diagnostic parameter is based on a reduction in scar autofluorescence, evaluated in the green spectral channel. The validity of the method has been tested on 110 postoperative scars from 56 patients suspected of non-melanoma skin cancer, with eight patients (13 scars) available for the repeated examination. The recurrence diagnosis within a scar has been made after two subsequent autofluorescence check-ups, representing the temporal difference between the scar autofluorescence amplitudes as a vector. The recognition of recurrence has been discussed to represent the significant deviations from the value of vector angle θ. This new autofluorescence-based method can be easily integrated into the postoperative monitoring of surgical scars and can help diagnose the recurrence of skin cancer from the early stage of scar development.

AB - This clinical study is a first attempt to use autofluorescence for recurrence diagnosis of skin cancer in postoperative scars. The proposed diagnostic parameter is based on a reduction in scar autofluorescence, evaluated in the green spectral channel. The validity of the method has been tested on 110 postoperative scars from 56 patients suspected of non-melanoma skin cancer, with eight patients (13 scars) available for the repeated examination. The recurrence diagnosis within a scar has been made after two subsequent autofluorescence check-ups, representing the temporal difference between the scar autofluorescence amplitudes as a vector. The recognition of recurrence has been discussed to represent the significant deviations from the value of vector angle θ. This new autofluorescence-based method can be easily integrated into the postoperative monitoring of surgical scars and can help diagnose the recurrence of skin cancer from the early stage of scar development.

KW - autofluorescence imaging

KW - recurrence

KW - scar

KW - skin cancer

KW - surgery

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M3 - Article

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M1 - e201900162

ER -

Autofluorescence imaging for recurrence detection in skin cancer postoperative scars

Abstract

Keywords*

Field of Science*

Publication Type*

UN SDGs

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