Biomechanical Properties of the Aorta in Neonates and Infants

Elīna Ligere (Corresponding Author), Normunds Sikora, Valts Ozolins, Smits Lauris, Inta Bergmane, Aris Lacis, Vladimir Kasyanov

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    Abstract

    The study to examine biomechanical properties of the aorta in neonates and the biomechanical properties of infantile aorta in case of different anastomoses used for surgical correction of aortic coarctation was started to detect the influence of the surgical technique on the biomechanics of infantile aorta and, therefore, the possible further changes in hemodynamics and blood flow. We analyzed seven specimens of native aorta and three specimens with the anastomosis end-to-end. We observed a non-linear relationship between stress and strain in the neonatal and infantile aorta. The strain of the end-to-end anastomosis was much smaller than in the native aorta. The modulus of elasticity of the aortic wall increased with the increase of inner pressure. However in the case of anastomosis end-to-end the modulus was almost constant and was relevant to the modulus of elasticity of the aorta with the inner pressure 100–120 mmHg. The results show that the stiffness of the anastomosis did not change with the changes in inner pressure which might affect hemodynamics.
    Original languageEnglish
    Title of host publicationAnalysis and Design of Biological Materials and Structures
    EditorsA Öchsner, L da Silva, L Altenbach
    Place of PublicationBerlin
    PublisherSpringer Heidelberg
    Pages125-132
    Volume 14
    ISBN (Electronic)978-3-642-22131-6
    ISBN (Print)978-3-642-22130-9
    DOIs
    Publication statusPublished - 1 Jan 2012

    Publication series

    NameAdvanced Structured Materials

    Keywords*

    • biomechanics
    • mechanical properties
    • neonatal aorta
    • Coarctation

    Field of Science*

    • 1.7 Other natural sciences

    Publication Type*

    • 3.2. Articles or chapters in other proceedings other than those included in 3.1., with an ISBN or ISSN code

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