Bioprinting: Directed tissue self-assembly

Vladimir Mironov, Vladimir Kasyanov, Roger Markwald

Research output: Contribution to journalArticlepeer-review


Bioprinting is a developing technology with potential for surpassing the traditional solid-scaffold based approach in tissue engineering. It is a biomedical application of rapid prototyping technology or computer aided layered additive biofabrication. The main concept of this technology is a directed tissue self assembly, which is the forming of tissue and next-level biological structures such as organs from single cells, cell aggregates and many more. Self-assembly is autonomous organization of components into patterns or structures without human intervention. This means precise automated robotic placement and positioning of cells and tissue spheroids according to the computer-aided design. The recent developments in the clinical bioimaging and ultrasound make it possible to discern the gross anatomical characteristics of organs, even while they are still inside the body. The rapid prototyping technology is stereolithography, using cells in a photo-sensitive hydrogel.

Original languageEnglish
Pages (from-to)S12-S17
Number of pages6
JournalChemical Engineering Progress
Issue number12
Publication statusPublished - Dec 2007

Field of Science*

  • 3.4 Medical biotechnology
  • 2.6 Medical engineering
  • 1.4 Chemical sciences

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database


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