Botanical ingredients in cosmetics: impact of novel formulation containing betula alba (birch) sap on biophysical parameters of the skin

Karīna Stasjuka, Aleksejs Zavorins

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Introduction. Gradual accumulation of different factors can disturb epidermal barrier function, corneocyte differentiation, lead to disintegration of collagen and elastic fibers, increase transepidermal water loss, reduce hydration and elastic recoil leading to dryness, laxity and reduced healing capacity of the skin. Active substances found in birch sap (organic and amino acids, betulin, micro- and macroelements) possess its use as ingredient with antioxidant, antiinflammatory, cell stimulating and water-replacing properties improving wound healing, epidermal barrier function and hydration. Aim of the study. The aim of this study was to evaluate impact of novel cosmetic formulation containing birch sap on biophysical parameters of the skin. Materials and Methods. Participants were asked to apply the test product on inner aspect of the left forearm twice a day. The right forearm was considered a control site. Instrumental assessment of hydration and viscoelasticity (R2, R5, R7) parameters was made using Corneometer CM 825 and Cutometer dual MPA580 (Courage & Khazaka, Germany) accordingly. Parameters were evaluated four times (before application as well as 1 hour, 5 days and 4 weeks after daily use of the product). Paired and independent sample T-test was used for analysis of collected data with p<0.05 considered statistically significant. Results. Statistically significant improvement in skin hydration level was observed regarding the experimental site when compared with the control site after 1 hour and 4 weeks (39.83 SD=30.86% vs. 0.83 SD=15.14%, p<0.001). There was statistically significant increase in moisture levels of both sites after 5 days, though percentage increase was significantly higher on the left site. Conclusions. Daily use of Betula alba sap containing cosmetics leads to good immediate as well as long term outcome providing marked improvement in moisture level of the skin.
Original languageEnglish
Title of host publicationProceedings of the 62nd International Scientific Conference of Daugavpils University
Subtitle of host publicationPart A. Natural Sciences
EditorsIrēna Kokina
Place of PublicationDaugavpils
PublisherDaugavpils University
ISBN (Print)978-9984-14-925-7
Publication statusPublished - 2020
Event62nd International Scientific Conference of Daugavpils University - Daugavpils, Latvia
Duration: 28 May 202029 May 2020
Conference number: 62


Conference62nd International Scientific Conference of Daugavpils University
OtherDaugavpils Universitātes 62. starptautiskā zinātniskā konference


  • dermatology
  • hydration
  • viscoelasticity
  • Betula alba
  • birch sap

Field of Science*

  • 1.6 Biological sciences
  • 3.2 Clinical medicine

Publication Type*

  • 3.2. Articles or chapters in other proceedings other than those included in 3.1., with an ISBN or ISSN code


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