Bullous Pemphigoid Associated with Acquired Hemophilia A

Bullous Pemphigus (BP) patients with skin of color are likely to present at a significantly younger age compared to Caucasian BP patients (mean ± standard deviation - 62.8 ± 3.3 years vs. 76.7 ± 1.4 years, respectively). Here, we would like to share our recent experience with a 77-year-old Vietnamese male patient who developed acquired hemophilia A within a few weeks after the diagnosis of BP. Apart from the older age at the time of presentation, our experience is unique in that the onset of acquired hemophilia is usually observed within a few months after the diagnosis of BP. With this case, we would like to alert clinicians and dermatologists to suspect acquired hemophilia A in patients with bullous pemphigoid who present with a constellation of symptoms including hemorrhagic bullae, hematoma, ecchymosis, and systemic bleeding.