TY - JOUR
T1 - Case report
T2 - Treatment-resistant schizophrenia with auto-aggressive compulsive behavior—Successful management with cariprazine
AU - Renemane, Lubova
AU - Rancāns, Elmārs
N1 - Funding Information:
Gedeon Richter covered the article submission fee. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article, or the decision to submit it for publication.
Publisher Copyright:
Copyright © 2023 Renemane and Rancans.
PY - 2023/6/29
Y1 - 2023/6/29
N2 - The present case report describes a patient with treatment-resistant schizophrenia and auto-aggressive compulsive behavior who was effectively treated with a third-generation antipsychotic medication, cariprazine. The diagnosis was made 12 years ago, and the patient has been hospitalized 14 times and undergone various antipsychotic treatments. Despite receiving both inpatient and outpatient care, the patient's response to treatment has been only partial, and he has been classified as a treatment-resistant case. Therefore, the patient was switched to cariprazine, which led to significant improvements in both positive and negative symptoms, as well as the complete reduction of auto-aggressive compulsive behavior. These improvements contributed to the patient's overall social functioning and the achievement of remission, while also avoiding polypharmacy and eliminating the metabolic side effects associated with previous treatments.
AB - The present case report describes a patient with treatment-resistant schizophrenia and auto-aggressive compulsive behavior who was effectively treated with a third-generation antipsychotic medication, cariprazine. The diagnosis was made 12 years ago, and the patient has been hospitalized 14 times and undergone various antipsychotic treatments. Despite receiving both inpatient and outpatient care, the patient's response to treatment has been only partial, and he has been classified as a treatment-resistant case. Therefore, the patient was switched to cariprazine, which led to significant improvements in both positive and negative symptoms, as well as the complete reduction of auto-aggressive compulsive behavior. These improvements contributed to the patient's overall social functioning and the achievement of remission, while also avoiding polypharmacy and eliminating the metabolic side effects associated with previous treatments.
KW - treatment-resistant schizophren
KW - cariprazi
KW - , aggressive compulsive behavi
KW - treatment of schizophren
KW - antipsychoti
UR - http://www.scopus.com/inward/record.url?scp=85165005132&partnerID=8YFLogxK
U2 - 10.3389/fpsyt.2023.1209077
DO - 10.3389/fpsyt.2023.1209077
M3 - Article
C2 - 37457773
SN - 1664-0640
VL - 14
JO - Frontiers in Psychiatry
JF - Frontiers in Psychiatry
M1 - 1209077
ER -